8G6W

Structure of WT E.coli 70S ribosome complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site ortho-aminobenzoic acid charged NH-tRNAPhe

This is a non-PDB format compatible entry.

Summary for 8G6W

• Entry DOI: 10.2210/pdb8g6w/pdb
• EMDB information: 29786
• Descriptor: 50S ribosomal protein L33, 30S ribosomal protein S5, 30S ribosomal protein S6, ... (64 entities in total)
• Functional Keywords: ribosome, non-natural monomers, aminobenzoic acids, unnatural monomers
• Biological source: Escherichia coli; More
• Total number of polymer chains: 55
• Total formula weight: 2209445.10

Authors

Majumdar, C.,Cate, J.H.D. (deposition date: 2023-02-16, release date: 2023-04-05, Last modification date: 2023-11-15)

• Primary citation: Majumdar, C.,Walker, J.A.,Francis, M.B.,Schepartz, A.,Cate, J.H.D.; Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.; Acs Cent.Sci., 9:1160-1169, 2023; PubMed: 37396857; DOI: 10.1021/acscentsci.3c00153

Experimental method

ELECTRON MICROSCOPY (2.02 Å)