Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, and Mn2+ bound

Summary for 1VBY

Related1DRZ 1CX0 1VBX 1VBZ 1VC0 1SJF 1VC5 1VC6 1VC7
DescriptorHepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A, MANGANESE (II) ION, ... (5 entities in total)
Functional Keywordshdv, ribozyme, rna, u1a, precursor, translation-rna complex, translation/rna
Biological sourceHomo sapiens (human)
Cellular locationNucleus P09012
Total number of polymer chains2
Total molecular weight36098.86
Ke, A.,Zhou, K.,Ding, F.,Cate, J.H.D.,Doudna, J.A. (deposition date: 2004-03-03, release date: 2004-05-18, Last modification date: 2011-07-13)
Primary citation
Ke, A.,Zhou, K.,Ding, F.,Cate, J.H.D.,Doudna, J.A.
A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429:201-205, 2004
PubMed: 15141216 (PDB entries with the same primary citation)
DOI: 10.1038/nature02522
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.284173.2%2.4%5.4%0.59MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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