8G6X

Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site meta-aminobenzoic acid charged NH-tRNAPhe

Summary for 8G6X

Entry DOI	10.2210/pdb8g6x/pdb
Related	8G6W 8G6Y
EMDB information	29786 29787 29788 29789 29790 29800 29807
Descriptor	23S rRNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (43 entities in total)
Functional Keywords	ribosome, non-natural monomers, aminobenzoic acids, unnatural monomers
Biological source	Escherichia coli More
Total number of polymer chains	34
Total formula weight	1417971.23
Authors	Majumdar, C.,Cate, J.H.D. (deposition date: 2023-02-16, release date: 2023-03-22, Last modification date: 2023-11-15)
Primary citation	Majumdar, C.,Walker, J.A.,Francis, M.B.,Schepartz, A.,Cate, J.H.D. Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome. Acs Cent.Sci., 9:1160-1169, 2023 Cited by PubMed: 37396857 DOI: 10.1021/acscentsci.3c00153 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.31 Å)

Structure validation