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8G6X

Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site meta-aminobenzoic acid charged NH-tRNAPhe

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(a)
23S rRNApolymer2904941811.61Escherichia coli
2B
(b)
5S rRNApolymer12038790.11GenBank (1273279017)Escherichia coli
3C
(c)
50S ribosomal protein L2polymer27329923.61UniProt (P60422)
Pfam (PF00181)
Pfam (PF03947)
Escherichia coliLarge ribosomal subunit protein uL2
4D
(d)
50S ribosomal protein L3polymer20922291.61UniProt (U9Y9G2)
Pfam (PF00297)
UniProt (by SIFTS) (P60438)
Escherichia coli
5E
(e)
50S ribosomal protein L4polymer20122121.61Pfam (PF00573)
UniProt (by SIFTS) (P60723)
Escherichia coli
6F
(f)
50S ribosomal protein L5polymer17920333.61UniProt (A0A829CFT8)
Pfam (PF00281)
Pfam (PF00673)
UniProt (by SIFTS) (P62399)
Escherichia coli
7G
(g)
50S ribosomal protein L6polymer17718932.81UniProt (A0A862ZNS7)
Pfam (PF00347)
UniProt (by SIFTS) (P0AG55)
Escherichia coli
8H
(h)
50S ribosomal protein L9polymer14915789.01UniProt (V0YZK9)
Pfam (PF01281)
Pfam (PF03948)
UniProt (by SIFTS) (P0A7R1)
Escherichia coli
9I
(i)
50S ribosomal protein L13polymer14216050.61UniProt (S1EW51)
Pfam (PF00572)
UniProt (by SIFTS) (P0AA10)
Escherichia coli
10J
(j)
50S ribosomal protein L14polymer12313565.11UniProt (S1NW45)
Pfam (PF00238)
UniProt (by SIFTS) (P0ADY3)
Escherichia coli
11K
(k)
50S ribosomal protein L15polymer14415008.51UniProt (A0A037Y8L6)
Pfam (PF00828)
UniProt (by SIFTS) (P02413)
Escherichia coli
12L
(l)
50S ribosomal protein L16polymer13615329.31Pfam (PF00252)
UniProt (by SIFTS) (P0ADY7)
Escherichia coli
13M
(m)
50S ribosomal protein L17polymer12714393.71UniProt (A0A1X3LC97)
Pfam (PF01196)
UniProt (by SIFTS) (P0AG44)
Escherichia coli
14N
(n)
50S ribosomal protein L18polymer11712794.71UniProt (E3PKY8)
Pfam (PF00861)
UniProt (by SIFTS) (P0C018)
Escherichia coli
15O
(o)
50S ribosomal protein L19polymer11513159.31UniProt (V0AJX1)
Pfam (PF01245)
UniProt (by SIFTS) (P0A7K6)
Escherichia coli
16P
(p)
50S ribosomal protein L20polymer11813528.01UniProt (B7MAS6)
Pfam (PF00453)
UniProt (by SIFTS) (P0A7L3)
Escherichia coli
17Q
(q)
Ribosomal protein L21polymer10311586.41UniProt (A0A829CSJ4)
Pfam (PF00829)
UniProt (by SIFTS) (P0AG48)
Escherichia coli
18R
(r)
50S ribosomal protein L22polymer11012253.41UniProt (P61175)
Pfam (PF00237)
Escherichia coliLarge ribosomal subunit protein uL22
19S
(s)
50S ribosomal protein L23polymer10011222.21UniProt (A0A829CFV1)
Pfam (PF00276)
UniProt (by SIFTS) (P0ADZ0)
Escherichia coli
20T
(t)
50S ribosomal protein L24polymer10411339.31UniProt (A0A1X3KWX7)
Pfam (PF00467)
Pfam (PF17136)
UniProt (by SIFTS) (P60624)
Escherichia coli
21U
(u)
50S ribosomal protein L25polymer9410713.51UniProt (D7XH79)
Pfam (PF01386)
UniProt (by SIFTS) (P68919)
Escherichia coli
22V
(v)
50S ribosomal protein L27polymer859146.51UniProt (P0A7L8)
Pfam (PF01016)
Escherichia coliLarge ribosomal subunit protein bL27
23W
(w)
50S ribosomal protein L28polymer789027.61UniProt (A0A1X3JA73)
Pfam (PF00830)
UniProt (by SIFTS) (P0A7M2)
Escherichia coli
24X
(x)
50S ribosomal protein L29polymer637286.51UniProt (D6IEL0)
Pfam (PF00831)
UniProt (by SIFTS) (P0A7M6)
Escherichia coli
25Y
(y)
50S ribosomal protein L30polymer596554.81UniProt (V0YKA9)
Pfam (PF00327)
UniProt (by SIFTS) (P0AG51)
Escherichia coli
26Z
(z)
50S ribosomal protein L32polymer576463.41UniProt (D7XI28)
Pfam (PF01783)
UniProt (by SIFTS) (P0A7N4)
Escherichia coli
27AA
(0)
50S ribosomal protein L33polymer556388.61UniProt (F4NQ61)
Pfam (PF00471)
UniProt (by SIFTS) (P0A7N9)
Escherichia coli
28BA
(1)
50S ribosomal protein L34polymer465397.51UniProt (B7MGC4)
Pfam (PF00468)
UniProt (by SIFTS) (P0A7P5)
Escherichia coli
29CA
(2)
50S ribosomal protein L35polymer657313.01UniProt (P0A7Q1)
Pfam (PF01632)
Escherichia coliLarge ribosomal subunit protein bL35,Ribosomal protein A
30DA
(3)
50S ribosomal protein L36polymer384377.41UniProt (A0A0E2L017)
Pfam (PF00444)
UniProt (by SIFTS) (P0A7Q6)
Escherichia coli
31EA
(4)
50S ribosomal protein L31polymer707887.11UniProt (P0A7M9)
Pfam (PF01197)
Escherichia coliLarge ribosomal subunit protein bL31-A
32FA
(Y)
A-site tRNA Phepolymer7624485.51GenBank (1315725308)Escherichia coli
33GA
(Z)
P-site tRNA fMetpolymer7624513.61GenBank (1804121330)Escherichia coli
34HA
(X)
mRNApolymer289036.41Escherichia coli
35AB, AC, AD, AE, AF...
(a, Z, b, c, d...)
MAGNESIUM IONnon-polymer24.3223Chemie (MG)
36AI, BI, CI, DI, EI...
(a)
SPERMIDINEnon-polymer145.217Chemie (SPD)
37MI
(a)
SPERMINEnon-polymer202.31Chemie (SPM)
38OI, PJ, RI, SI, SJ...
(a, c, e)
POTASSIUM IONnon-polymer39.17Chemie (K)
39VI
(a)
N-FORMYLMETHIONINEnon-polymer177.21Chemie (FME)
40VJ, WJ
(3, 4)
ZINC IONnon-polymer65.42Chemie (ZN)
41XJ
(Y)
3-aminobenzamidenon-polymer136.21Chemie (3AB)
42ZJ
(Z)
3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate)non-polymer346.21Chemie (8AN)
43AL, BK, BL, CK, DK...
(3, a, Z, b, c...)
waterwater18.03462Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains34
Total formula weight1408815.6
Non-Polymers*Number of molecules253
Total formula weight9155.6
All*Total formula weight1417971.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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