2XCO

The 3.1A crystal structure of the catalytic core (B'A' region) of Staphylococcus aureus DNA Gyrase

Summary for 2XCO

Entry DOI	10.2210/pdb2xco/pdb
Related	2XCQ 2XCR 2XCS 2XCT
Descriptor	DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A, CALCIUM ION (3 entities in total)
Functional Keywords	isomerase
Biological source	STAPHYLOCOCCUS AUREUS
Cellular location	Cytoplasm (Potential): Q99XG5
Total number of polymer chains	1
Total formula weight	82384.98
Authors	Bax, B.D.,Chan, P.F.,Eggleston, D.S.,Fosberry, A.,Gentry, D.R.,Gorrec, F.,Giordano, I.,Hann, M.M.,Hennessy, A.,Hibbs, M.,Huang, J.,Jones, E.,Jones, J.,Brown, K.K.,Lewis, C.J.,May, E.W.,Singh, O.,Spitzfaden, C.,Shen, C.,Shillings, A.,Theobald, A.F.,Wohlkonig, A.,Pearson, N.D.,Gwynn, M.N. (deposition date: 2010-04-24, release date: 2010-08-04, Last modification date: 2011-07-13)
Primary citation	Bax, B.D.,Chan, P.F.,Eggleston, D.S.,Fosberry, A.,Gentry, D.R.,Gorrec, F.,Giordano, I.,Hann, M.M.,Hennessy, A.,Hibbs, M.,Huang, J.,Jones, E.,Jones, J.,Brown, K.K.,Lewis, C.J.,May, E.W.,Saunders, M.R.,Singh, O.,Spitzfaden, C.,Shen, C.,Shillings, A.,Theobald, A.F.,Wohlkonig, A.,Pearson, N.D.,Gwynn, M.N. Type Iia Topoisomerase Inhibition by a New Class of Antibacterial Agents. Nature, 466:935-, 2010 Cited by PubMed: 20686482 DOI: 10.1038/NATURE09197 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation