7S0F

Isoproterenol bound beta1 adrenergic receptor in complex with heterotrimeric Gi protein

Summary for 7S0F

Entry DOI	10.2210/pdb7s0f/pdb
EMDB information	24789
Descriptor	Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1,, ... (5 entities in total)
Functional Keywords	gi protein, gpcr-gi complex, agonist, signaling protein
Biological source	Meleagris gallopavo More
Total number of polymer chains	4
Total formula weight	146447.81
Authors	Paknejad, N.,Alegre, K.O.,Su, M.,Lou, J.S.,Huang, J.,Jordan, K.D.,Eng, E.T.,Meyerson, J.R.,Hite, R.K.,Huang, X.Y. (deposition date: 2021-08-30, release date: 2021-11-17, Last modification date: 2021-12-01)
Primary citation	Alegre, K.O.,Paknejad, N.,Su, M.,Lou, J.S.,Huang, J.,Jordan, K.D.,Eng, E.T.,Meyerson, J.R.,Hite, R.K.,Huang, X.Y. Structural basis and mechanism of activation of two different families of G proteins by the same GPCR. Nat.Struct.Mol.Biol., 28:936-944, 2021 Cited by PubMed: 34759376 DOI: 10.1038/s41594-021-00679-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.96 Å)

Structure validation