2XKK

CRYSTAL STRUCTURE OF MOXIFLOXACIN, DNA, and A. BAUMANNII TOPO IV (PARE-PARC FUSION TRUNCATE)

Summary for 2XKK

Related2XKJ
DescriptorTOPOISOMERASE IV, DNA, MAGNESIUM ION, ... (6 entities in total)
Functional Keywordsisomerase-dna-antibiotic complex, type iia topoisomerase, quinolone, antibacterial agent, isomerase/dna/antibiotic
Biological sourceACINETOBACTER BAUMANNII
More
Total number of polymer chains4
Total molecular weight194147.1
Authors
Wohlkonig, A.,Chan, P.F.,Fosberry, A.P.,Homes, P.,Huang, J.,Kranz, M.,Leydon, V.R.,Miles, T.J.,Pearson, N.D.,Perera, R.L.,Shillings, A.J.,Gwynn, M.N.,Bax, B.D. (deposition date: 2010-07-08, release date: 2010-09-01, Last modification date: 2011-10-12)
Primary citation
Wohlkonig, A.,Chan, P.F.,Fosberry, A.P.,Homes, P.,Huang, J.,Kranz, M.,Leydon, V.R.,Miles, T.J.,Pearson, N.D.,Perera, R.L.,Shillings, A.J.,Gwynn, M.N.,Bax, B.D.
Structural Basis of Quinolone Inhibition of Type Iia Topoisomerases and Target-Mediated Resistance
Nat.Struct.Mol.Biol., 17:1152-, 2010
PubMed: 20802486 (PDB entries with the same primary citation)
DOI: 10.1038/NSMB.1892
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.25 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.263272.5%10.3%2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload