2VG7
Crystal structures of HIV-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors
2VG7 の概要
エントリーDOI | 10.2210/pdb2vg7/pdb |
関連するPDBエントリー | 1AJV 1AJX 1AXA 1BQM 1BQN 1D4H 1D4I 1D4J 1DLO 1DW6 1EBK 1EBW 1EBY 1EBZ 1EC0 1EC1 1EC2 1EC3 1EET 1HBV 1HEF 1HEG 1HIH 1HMV 1HNI 1HNV 1HOS 1HPS 1HPZ 1HQE 1HQU 1HRH 1HTE 1HTF 1HTG 1HVK 1HVP 1HVU 1HYS 1IKV 1IKW 1IKX 1IKY 1J5O 1MER 1MES 1MET 1MEU 1N5Y 1N6Q 1QE1 1QMC 1R0A 1RDH 1RTD 1RVL 1RVM 1RVN 1RVO 1RVP 1RVQ 1RVR 1S6P 1S6Q 1S9E 1S9G 1SBG 1SUQ 1SV5 1T03 1T05 1TV6 1TVR 1UWB 1W5V 1W5W 1W5X 1W5Y 2B5J 2B6A 2BAN 2BE2 2HMI 2UXZ 2UY0 2VG5 2VG6 3HVT 3TLH |
分子名称 | REVERSE TRANSCRIPTASE/RIBONUCLEASE H, P51 RT, O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] (4-iodophenyl)thiocarbamate, ... (4 entities in total) |
機能のキーワード | dna-directed dna polymerase, thiocarbamates, phosphorylation, dna integration, magnesium, zinc-finger, rna-binding, transferase, lipoprotein, core protein, endonuclease, metal-binding, zinc, aids, hiv-1, virion, nucleus, membrane, aspartyl protease, capsid maturation, multifunctional enzyme, rna-directed dna polymerase, reverse transcriptase, nucleotidyltransferase, dna recombination, viral nucleoprotein, protease, nuclease, myristate, hydrolase, cytoplasm, non-nucleoside reverse transcriptase inhibitors |
由来する生物種 | HUMAN IMMUNODEFICIENCY VIRUS 1 (HIV-1) 詳細 |
細胞内の位置 | Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03366 P03366 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 114669.35 |
構造登録者 | Spallarossa, A.,Cesarini, S.,Ranise, A.,Ponassi, M.,Unge, T.,Bolognesi, M. (登録日: 2007-11-08, 公開日: 2007-12-11, 最終更新日: 2024-05-08) |
主引用文献 | Spallarossa, A.,Cesarini, S.,Ranise, A.,Ponassi, M.,Unge, T.,Bolognesi, M. Crystal Structures of HIV-1 Reverse Transcriptase Complexes with Thiocarbamate Non-Nucleoside Inhibitors. Biochem.Biophys.Res.Commun., 365:764-, 2008 Cited by PubMed: 18035053DOI: 10.1016/J.BBRC.2007.11.036 主引用文献が同じPDBエントリー |
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