2B6A
Crystal structure of HIV-1 reverse transcriptase (RT) in complex with THR-50
Summary for 2B6A
Entry DOI | 10.2210/pdb2b6a/pdb |
Related | 2B5J |
Descriptor | Reverse transcriptase p66 subunit, Reverse transcriptase p51 subunit, 1-(2,6-DIFLUOROBENZYL)-2-(2,6-DIFLUOROPHENYL)-4-METHYL-1H-BENZIMIDAZOLE (3 entities in total) |
Functional Keywords | aids, hiv, drug design, reverse transcriptase, rt, protein-inhibitor complex, transferase |
Biological source | Human immunodeficiency virus 1 More |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03366 P03366 |
Total number of polymer chains | 2 |
Total formula weight | 115153.07 |
Authors | Morningstar, M.L.,Roth, T.,Smith, M.K.,Zajac, M.,Watson, K.,Buckheit, R.W.,Das, K.,Zhang, W.,Arnold, E.,Michejda, C.J. (deposition date: 2005-09-30, release date: 2005-11-01, Last modification date: 2023-08-23) |
Primary citation | Morningstar, M.L.,Roth, T.,Smith, M.K.,Zajac, M.,Watson, K.,Buckheit, R.W.,Das, K.,Zhang, W.,Arnold, E.,Michejda, C.J. Crystal structure of HIV-1 reverse transcriptase (RT) in complex with THR-50 TO BE PUBLISHED, |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
Download full validation report