2VG7
Crystal structures of HIV-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | REVERSE TRANSCRIPTASE/RIBONUCLEASE H | polymer | 557 | 64161.5 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) In PDB | HUMAN IMMUNODEFICIENCY VIRUS 1 (HIV-1) | HIV-1 REVERSE TRANSCRIPTASE, P66 RT |
| 2 | B | P51 RT | polymer | 428 | 50055.6 | 1 | UniProt (P03366) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) In PDB | HUMAN IMMUNODEFICIENCY VIRUS 1 (HIV-1) | HIV-1 REVERSE TRANSCRIPTASE |
| 3 | A | O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] (4-iodophenyl)thiocarbamate | non-polymer | 452.3 | 1 | Chemie (NNI) | |||
| 4 | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 114217.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 452.3 | |
| All* | Total formula weight | 114669.4 |
