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2VG7

Crystal structures of HIV-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
REVERSE TRANSCRIPTASE/RIBONUCLEASE Hpolymer55764161.51UniProt (P03366)
Pfam (PF00078)
Pfam (PF06817)
Pfam (PF06815)
Pfam (PF00075)
HUMAN IMMUNODEFICIENCY VIRUS 1 (HIV-1)HIV-1 REVERSE TRANSCRIPTASE, P66 RT
2B
(B)
P51 RTpolymer42850055.61UniProt (P03366)
Pfam (PF00078)
Pfam (PF06817)
Pfam (PF06815)
HUMAN IMMUNODEFICIENCY VIRUS 1 (HIV-1)HIV-1 REVERSE TRANSCRIPTASE
3C
(A)
O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] (4-iodophenyl)thiocarbamatenon-polymer452.31Chemie (NNI)
4D, E
(A, B)
waterwater18.046Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight114217.1
Non-Polymers*Number of molecules1
Total formula weight452.3
All*Total formula weight114669.4
*Water molecules are not included.

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PDB entries from 2025-07-02

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