2VG7

Crystal structures of HIV-1 reverse transcriptase complexes with thiocarbamate non-nucleoside inhibitors

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	MAX II BEAMLINE I711
Synchrotron site	MAX II
Beamline	I711
Temperature [K]	100
Detector technology	CCD
Detector	MARRESEARCH
Spacegroup name	C 2 2 21
Unit cell lengths	119.944, 156.996, 154.420
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	20.000 - 2.820
R-factor	0.259
Rwork	0.255
R-free	0.33300
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.003
RMSD bond angle	0.614
Phasing software	AMoRE
Refinement software	REFMAC (5.2.0005)

Data quality characteristics

	Overall
Low resolution limit [Å]	20.000
High resolution limit [Å]	2.800
Rmerge	0.070
Number of reflections	35517
Completeness [%]	81.1
Redundancy	2

Crystallization Conditions

crystal ID	method	pH	temperature	details
1