1AJX
HIV-1 PROTEASE IN COMPLEX WITH THE CYCLIC UREA INHIBITOR AHA001
Summary for 1AJX
| Entry DOI | 10.2210/pdb1ajx/pdb |
| Descriptor | HIV-1 PROTEASE, AHA001 (3 entities in total) |
| Functional Keywords | protease, aspartyl protease, non-peptide inhibitor, drug design, hiv-1 |
| Biological source | Human immunodeficiency virus 1 |
| Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03366 |
| Total number of polymer chains | 2 |
| Total formula weight | 22146.15 |
| Authors | Backbro, K.,Unge, T. (deposition date: 1997-05-11, release date: 1997-09-17, Last modification date: 2023-08-02) |
| Primary citation | Backbro, K.,Lowgren, S.,Osterlund, K.,Atepo, J.,Unge, T.,Hulten, J.,Bonham, N.M.,Schaal, W.,Karlen, A.,Hallberg, A. Unexpected binding mode of a cyclic sulfamide HIV-1 protease inhibitor. J.Med.Chem., 40:898-902, 1997 Cited by PubMed: 9083478DOI: 10.1021/jm960588d PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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