6BRK
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THE SAM DOMAIN OF MOUSE SAMHD1 IS CRITICAL FOR ITS ACTIVATION AND REGULATION
Descriptor:Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Buzovetsky, O., Tang, C., Knecht, K.M., Antonucci, J.M., Wu, L., Ji, X., Xiong, Y.
Deposit date:2017-11-30
Release date:2018-02-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The SAM domain of mouse SAMHD1 is critical for its activation and regulation.
Nat Commun, 9, 2018
6BRH
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THE SAM DOMAIN OF MOUSE SAMHD1 IS CRITICAL FOR ITS ACTIVATION AND REGULATION
Descriptor:Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, MAGNESIUM ION, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE
Authors:Buzovetsky, O., Tang, C., Knecht, K.M., Antonucci, J.M., Wu, L., Ji, X., Xiong, Y.
Deposit date:2017-11-30
Release date:2018-02-14
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The SAM domain of mouse SAMHD1 is critical for its activation and regulation.
Nat Commun, 9, 2018
6BRG
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THE SAM DOMAIN OF MOUSE SAMHD1 IS CRITICAL FOR ITS ACTIVATION AND REGULATION
Descriptor:Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, MAGNESIUM ION
Authors:Buzovetsky, O., Tang, C., Knecht, K.M., Antonucci, J.M., Wu, L., Ji, X., Xiong, Y.
Deposit date:2017-11-30
Release date:2018-02-14
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The SAM domain of mouse SAMHD1 is critical for its activation and regulation.
Nat Commun, 9, 2018
5ZRZ
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CRYSTAL STRUCTURE OF EPHA5/SAMD5 COMPLEX
Descriptor:Ephrin type-A receptor 5, Sterile alpha motif domain-containing protein 5
Authors:Wang, Y., Shang, Y., Li, J., Chen, W., Li, G., Wan, J., Liu, W., Zhang, M.
Deposit date:2018-04-25
Release date:2018-05-30
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
5ZRY
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CRYSTAL STRUCTURE OF EPHA6/ODIN COMPLEX
Descriptor:Ankyrin repeat and SAM domain-containing protein 1A,Ephrin type-A receptor 6, SULFATE ION, GLYCEROL, ...
Authors:Wang, Y., Shang, Y., Li, J., Chen, W., Li, G., Wan, J., Liu, W., Zhang, M.
Deposit date:2018-04-25
Release date:2018-05-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Specific Eph receptor-cytoplasmic effector signaling mediated by SAM-SAM domain interactions.
Elife, 7, 2018
5KNI
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CRYSTAL STRUCTURE OF THE WILD-TYPE SAM DOMAIN OF HUMAN TANKYRASE-1
Descriptor:Tankyrase-1
Authors:Pascal, J.M., McCauley, M., Langelier, M.F., Riccio, A.A.
Deposit date:2016-06-28
Release date:2016-08-31
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Tankyrase Sterile alpha Motif Domain Polymerization Is Required for Its Role in Wnt Signaling.
Structure, 24, 2016
5JU5
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CRYSTAL STRUCTURE OF THE HUMAN TANKYRASE 1 (TNKS) SAM DOMAIN (D1055R), CRYSTAL FORM 1
Descriptor:Tankyrase-1
Authors:Guetter, S., Mariotti, L., Cronin, N.
Deposit date:2016-05-10
Release date:2016-08-03
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-beta-Catenin Signaling.
Mol.Cell, 63, 2016
5JTI
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CRYSTAL STRUCTURE OF THE HUMAN TANKYRASE 1 (TNKS) SAM DOMAIN (D1055R), CRYSTAL FORM 2
Descriptor:Tankyrase-1
Authors:Guetter, S., Mariotti, L., Cronin, N.
Deposit date:2016-05-09
Release date:2016-08-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-beta-Catenin Signaling.
Mol.Cell, 63, 2016
5JRT
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CRYSTAL STRUCTURE OF THE HUMAN TANKYRASE 2 (TNKS2) SAM DOMAIN (DH902/924RE)
Descriptor:Tankyrase-2
Authors:Guettler, S., Mariotti, L., Cronin, N.
Deposit date:2016-05-06
Release date:2016-08-03
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-beta-Catenin Signaling.
Mol.Cell, 63, 2016
5AO0
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CRYSTAL STRUCTURE OF HUMAN SAMHD1 (AMINO ACID RESIDUES 41-583) BOUND TO DDGTP
Descriptor:DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Schwefel, D., Taylor, I.A.
Deposit date:2015-09-09
Release date:2015-10-14
Method:X-RAY DIFFRACTION (3.731 Å)
Cite:Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction.
Plos Pathog., 11, 2015
3TAD
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CRYSTAL STRUCTURE OF THE LIPRIN-ALPHA/LIPRIN-BETA COMPLEX
Descriptor:Liprin-alpha-2, Liprin-beta-1, GLYCEROL
Authors:Wei, Z., Zheng, S., Yu, C., Zhang, M.
Deposit date:2011-08-04
Release date:2011-10-12
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Liprin-mediated large signaling complex organization revealed by the liprin-alpha/CASK and liprin-alpha/liprin-beta complex structures
Mol.Cell, 43, 2011
3TAC
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CRYSTAL STRUCTURE OF THE LIPRIN-ALPHA/CASK COMPLEX
Descriptor:Peripheral plasma membrane protein CASK, Liprin-alpha-2, SULFATE ION, ...
Authors:Wei, Z., Zheng, S., Yu, C., Zhang, M.
Deposit date:2011-08-03
Release date:2011-10-12
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Liprin-mediated large signaling complex organization revealed by the liprin-alpha/CASK and liprin-alpha/liprin-beta complex structures
Mol.Cell, 43, 2011
3H8M
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SAM DOMAIN OF HUMAN EPHRIN TYPE-A RECEPTOR 7 (EPHA7)
Descriptor:Ephrin type-A receptor 7
Authors:Walker, J.R., Yermekbayeva, L., Butler-Cole, C., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2009-04-29
Release date:2009-05-26
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:SAM Domain of Human Ephrin Type-A Receptor 7 (Epha7)
To be Published
3BS7
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CRYSTAL STRUCTURE OF THE STERILE ALPHA MOTIF (SAM) DOMAIN OF HYPHEN/AVEUGLE
Descriptor:Protein aveugle
Authors:Rajakulendran, T., Sicheri, F.
Deposit date:2007-12-22
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.
Proc.Natl.Acad.Sci.USA, 105, 2008
3BS5
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CRYSTAL STRUCTURE OF HCNK2-SAM/DHYP-SAM COMPLEX
Descriptor:Protein aveugle, Connector enhancer of kinase suppressor of ras 2
Authors:Rajakulendran, T., Ceccarelli, D.F., Kurinov, I., Sicheri, F.
Deposit date:2007-12-22
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.
Proc.Natl.Acad.Sci.USA, 105, 2008
3BQ7
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SAM DOMAIN OF DIACYLGLYCEROL KINASE DELTA1 (E35G)
Descriptor:Diacylglycerol kinase delta
Authors:Knight, M.J., Bowie, J.U., Sawaya, M.R.
Deposit date:2007-12-19
Release date:2008-03-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Regulation of Enzyme Localization by Polymerization: Polymer Formation by the SAM Domain of Diacylglycerol Kinase delta1
Structure, 16, 2008
2L5Y
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NMR STRUCTURE OF CALCIUM-LOADED STIM2 EF-SAM.
Descriptor:Stromal interaction molecule 2, CALCIUM ION
Authors:Zheng, L., Stathopulos, P.B., Ikura, M.
Deposit date:2010-11-09
Release date:2011-01-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry.
Proc.Natl.Acad.Sci.USA, 108, 2011
2KG5
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NMR SOLUTION STRUCTURE OF ARAP3-SAM
Descriptor:Arf-GAP, Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Authors:Leone, M., Pellecchia, M.
Deposit date:2009-03-05
Release date:2009-11-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Sam domain of the lipid phosphatase Ship2 adopts a common model to interact with Arap3-Sam and EphA2-Sam.
Bmc Struct.Biol., 9, 2009
2K60
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NMR STRUCTURE OF CALCIUM-LOADED STIM1 EF-SAM
Descriptor:PROTEIN (Stromal interaction molecule 1), CALCIUM ION
Authors:Stathopulos, P.B., Ikura, M.
Deposit date:2008-07-02
Release date:2008-10-07
Last modified:2013-07-24
Method:SOLUTION NMR
Cite:Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry.
Cell(Cambridge,Mass.), 135, 2008
2JW2
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VALIDATION OF INTER-HELICAL ORIENTATION OF THE STERIL-ALPHA-MOTIF OF HUMAN DELETED IN LIVER CANCER 2 BY RESIDUAL DIPOLAR COUPLINGS
Descriptor:StAR-related lipid transfer protein 13
Authors:Li, H., Sze, K., Fung, K.
Deposit date:2007-10-03
Release date:2008-10-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Validation of inter-helical orientation of the steril-alpha-motif of human deleted in liver cancer 2 by residual dipolar couplings
To be Published
2H80
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NMR STRUCTURES OF SAM DOMAIN OF DELETED IN LIVER CANCER 2 (DLC2)
Descriptor:StAR-related lipid transfer protein 13
Authors:Li, H.Y., Fung, K.L., Jin, D.Y., Chung, S.S., Ko, B.C., Sun, H.Z.
Deposit date:2006-06-06
Release date:2007-05-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures, dynamics, and lipid-binding of the sterile alpha-motif domain of the deleted in liver cancer 2
Proteins, 67, 2007
2GYT
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SOLUTION STRUCTURE OF THE SAM (STERILE ALPHA MOTIF) DOMAIN OF DLC1 (DELETED IN LIVER CANCER 1)
Descriptor:Deleted in liver cancer 1 protein, isoform 2
Authors:Yang, S.
Deposit date:2006-05-10
Release date:2007-04-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The SAM domain of the RhoGAP DLC1 binds EF1A1 to regulate cell migration
J.Cell.Sci., 122, 2009
2GLE
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SOLUTION STRUCTURE OF NEURABIN SAM DOMAIN
Descriptor:Neurabin-1
Authors:Ju, T., Hudak, J., Peti, W.
Deposit date:2006-04-04
Release date:2007-03-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural characterization of the neurabin SAM domain
TO BE PUBLISHED
2FE9
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SOLUTION STRUCTURE OF THE VTS1 SAM DOMAIN IN THE PRESENCE OF RNA
Descriptor:Protein VTS1
Authors:Edwards, T.A., Butterwick, J.A., Palmer, A.G., Aggarwal, A.K.
Deposit date:2005-12-15
Release date:2006-01-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the Vts1 SAM Domain in the Presence of RNA.
J.Mol.Biol., 356, 2006
2F8K
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SEQUENCE SPECIFIC RECOGNITION OF RNA HAIRPINS BY THE SAM DOMAIN OF VTS1
Descriptor:5'-R(*UP*AP*AP*UP*CP*UP*UP*UP*GP*AP*CP*AP*GP*AP*UP*U)-3', Protein VTS1
Authors:Aviv, T., Lin, Z., Ben-Ari, G., Smibert, C.A., Sicheri, F.
Deposit date:2005-12-02
Release date:2006-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p.
Nat.Struct.Mol.Biol., 13, 2006
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