8TDW
ssRNA bound SAMHD1 T open
Summary for 8TDW
Entry DOI | 10.2210/pdb8tdw/pdb |
EMDB information | 41175 |
Descriptor | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, RNA (5'-R(P*CP*CP*GP*GP*CP*C)-3'), RNA (5'-R(P*CP*CP*GP*AP*CP*C)-3'), ... (4 entities in total) |
Functional Keywords | deoxynucleoside triphosphate triphosphohydrolase, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 293049.71 |
Authors | |
Primary citation | Orris, B.,Sung, M.W.,Bhat, S.,Xu, Y.,Huynh, K.W.,Han, S.,Johnson, D.C.,Bosbach, B.,Shields, D.J.,Stivers, J.T. Guanine-containing ssDNA and RNA induce dimeric and tetrameric structural forms of SAMHD1. Nucleic Acids Res., 51:12443-12458, 2023 Cited by PubMed: 37930833DOI: 10.1093/nar/gkad971 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.04 Å) |
Structure validation
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