7QG0

Inhibitor-induced hSARM1 duplex

Summary for 7QG0

• Entry DOI: 10.2210/pdb7qg0/pdb
• EMDB information: 13951
• Descriptor: NAD(+) hydrolase SARM1 (1 entity in total)
• Functional Keywords: sarm1, inhibitor, axon, degeneration, apoptosis
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 16
• Total formula weight: 1279540.13

Authors

Zalk, R.,Kahzma, T.,Guez-Haddad, J. (deposition date: 2021-12-07, release date: 2022-12-21, Last modification date: 2023-01-11)

• Primary citation: Khazma, T.,Golan-Vaishenker, Y.,Guez-Haddad, J.,Grossman, A.,Sain, R.,Weitman, M.,Plotnikov, A.,Zalk, R.,Hons, M.,Opatowsky, Y.; A duplex structure of SARM1 octamers stabilized by a new inhibitor.; Cell.Mol.Life Sci., 80:16-16, 2022; PubMed: 36564647; DOI: 10.1007/s00018-022-04641-3

Experimental method

ELECTRON MICROSCOPY (4.02 Å)