7QG0

Inhibitor-induced hSARM1 duplex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002376	biological_process	immune system process
A	0003690	molecular_function	double-stranded DNA binding
A	0003953	molecular_function	NAD+ nucleosidase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005741	cellular_component	mitochondrial outer membrane
A	0005829	cellular_component	cytosol
A	0005874	cellular_component	microtubule
A	0007165	biological_process	signal transduction
A	0007399	biological_process	nervous system development
A	0009986	cellular_component	cell surface
A	0015630	cellular_component	microtubule cytoskeleton
A	0016787	molecular_function	hydrolase activity
A	0019677	biological_process	NAD+ catabolic process
A	0030154	biological_process	cell differentiation
A	0030424	cellular_component	axon
A	0030425	cellular_component	dendrite
A	0031594	cellular_component	neuromuscular junction
A	0032991	cellular_component	protein-containing complex
A	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
A	0035591	molecular_function	signaling adaptor activity
A	0043068	biological_process	positive regulation of programmed cell death
A	0045087	biological_process	innate immune response
A	0045202	cellular_component	synapse
A	0048678	biological_process	response to axon injury
A	0048814	biological_process	regulation of dendrite morphogenesis
A	0050135	molecular_function	NADP+ nucleosidase activity
A	0050877	biological_process	nervous system process
A	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
A	0070585	biological_process	protein localization to mitochondrion
A	0098978	cellular_component	glutamatergic synapse
A	0099010	biological_process	modification of postsynaptic structure
A	0099243	cellular_component	extrinsic component of synaptic membrane
A	1905806	biological_process	regulation of synapse pruning
B	0002376	biological_process	immune system process
B	0003690	molecular_function	double-stranded DNA binding
B	0003953	molecular_function	NAD+ nucleosidase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005741	cellular_component	mitochondrial outer membrane
B	0005829	cellular_component	cytosol
B	0005874	cellular_component	microtubule
B	0007165	biological_process	signal transduction
B	0007399	biological_process	nervous system development
B	0009986	cellular_component	cell surface
B	0015630	cellular_component	microtubule cytoskeleton
B	0016787	molecular_function	hydrolase activity
B	0019677	biological_process	NAD+ catabolic process
B	0030154	biological_process	cell differentiation
B	0030424	cellular_component	axon
B	0030425	cellular_component	dendrite
B	0031594	cellular_component	neuromuscular junction
B	0032991	cellular_component	protein-containing complex
B	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
B	0035591	molecular_function	signaling adaptor activity
B	0043068	biological_process	positive regulation of programmed cell death
B	0045087	biological_process	innate immune response
B	0045202	cellular_component	synapse
B	0048678	biological_process	response to axon injury
B	0048814	biological_process	regulation of dendrite morphogenesis
B	0050135	molecular_function	NADP+ nucleosidase activity
B	0050877	biological_process	nervous system process
B	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
B	0070585	biological_process	protein localization to mitochondrion
B	0098978	cellular_component	glutamatergic synapse
B	0099010	biological_process	modification of postsynaptic structure
B	0099243	cellular_component	extrinsic component of synaptic membrane
B	1905806	biological_process	regulation of synapse pruning
C	0002376	biological_process	immune system process
C	0003690	molecular_function	double-stranded DNA binding
C	0003953	molecular_function	NAD+ nucleosidase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005741	cellular_component	mitochondrial outer membrane
C	0005829	cellular_component	cytosol
C	0005874	cellular_component	microtubule
C	0007165	biological_process	signal transduction
C	0007399	biological_process	nervous system development
C	0009986	cellular_component	cell surface
C	0015630	cellular_component	microtubule cytoskeleton
C	0016787	molecular_function	hydrolase activity
C	0019677	biological_process	NAD+ catabolic process
C	0030154	biological_process	cell differentiation
C	0030424	cellular_component	axon
C	0030425	cellular_component	dendrite
C	0031594	cellular_component	neuromuscular junction
C	0032991	cellular_component	protein-containing complex
C	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
C	0035591	molecular_function	signaling adaptor activity
C	0043068	biological_process	positive regulation of programmed cell death
C	0045087	biological_process	innate immune response
C	0045202	cellular_component	synapse
C	0048678	biological_process	response to axon injury
C	0048814	biological_process	regulation of dendrite morphogenesis
C	0050135	molecular_function	NADP+ nucleosidase activity
C	0050877	biological_process	nervous system process
C	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
C	0070585	biological_process	protein localization to mitochondrion
C	0098978	cellular_component	glutamatergic synapse
C	0099010	biological_process	modification of postsynaptic structure
C	0099243	cellular_component	extrinsic component of synaptic membrane
C	1905806	biological_process	regulation of synapse pruning
D	0002376	biological_process	immune system process
D	0003690	molecular_function	double-stranded DNA binding
D	0003953	molecular_function	NAD+ nucleosidase activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005741	cellular_component	mitochondrial outer membrane
D	0005829	cellular_component	cytosol
D	0005874	cellular_component	microtubule
D	0007165	biological_process	signal transduction
D	0007399	biological_process	nervous system development
D	0009986	cellular_component	cell surface
D	0015630	cellular_component	microtubule cytoskeleton
D	0016787	molecular_function	hydrolase activity
D	0019677	biological_process	NAD+ catabolic process
D	0030154	biological_process	cell differentiation
D	0030424	cellular_component	axon
D	0030425	cellular_component	dendrite
D	0031594	cellular_component	neuromuscular junction
D	0032991	cellular_component	protein-containing complex
D	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
D	0035591	molecular_function	signaling adaptor activity
D	0043068	biological_process	positive regulation of programmed cell death
D	0045087	biological_process	innate immune response
D	0045202	cellular_component	synapse
D	0048678	biological_process	response to axon injury
D	0048814	biological_process	regulation of dendrite morphogenesis
D	0050135	molecular_function	NADP+ nucleosidase activity
D	0050877	biological_process	nervous system process
D	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
D	0070585	biological_process	protein localization to mitochondrion
D	0098978	cellular_component	glutamatergic synapse
D	0099010	biological_process	modification of postsynaptic structure
D	0099243	cellular_component	extrinsic component of synaptic membrane
D	1905806	biological_process	regulation of synapse pruning
E	0002376	biological_process	immune system process
E	0003690	molecular_function	double-stranded DNA binding
E	0003953	molecular_function	NAD+ nucleosidase activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005741	cellular_component	mitochondrial outer membrane
E	0005829	cellular_component	cytosol
E	0005874	cellular_component	microtubule
E	0007165	biological_process	signal transduction
E	0007399	biological_process	nervous system development
E	0009986	cellular_component	cell surface
E	0015630	cellular_component	microtubule cytoskeleton
E	0016787	molecular_function	hydrolase activity
E	0019677	biological_process	NAD+ catabolic process
E	0030154	biological_process	cell differentiation
E	0030424	cellular_component	axon
E	0030425	cellular_component	dendrite
E	0031594	cellular_component	neuromuscular junction
E	0032991	cellular_component	protein-containing complex
E	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
E	0035591	molecular_function	signaling adaptor activity
E	0043068	biological_process	positive regulation of programmed cell death
E	0045087	biological_process	innate immune response
E	0045202	cellular_component	synapse
E	0048678	biological_process	response to axon injury
E	0048814	biological_process	regulation of dendrite morphogenesis
E	0050135	molecular_function	NADP+ nucleosidase activity
E	0050877	biological_process	nervous system process
E	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
E	0070585	biological_process	protein localization to mitochondrion
E	0098978	cellular_component	glutamatergic synapse
E	0099010	biological_process	modification of postsynaptic structure
E	0099243	cellular_component	extrinsic component of synaptic membrane
E	1905806	biological_process	regulation of synapse pruning
F	0002376	biological_process	immune system process
F	0003690	molecular_function	double-stranded DNA binding
F	0003953	molecular_function	NAD+ nucleosidase activity
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005741	cellular_component	mitochondrial outer membrane
F	0005829	cellular_component	cytosol
F	0005874	cellular_component	microtubule
F	0007165	biological_process	signal transduction
F	0007399	biological_process	nervous system development
F	0009986	cellular_component	cell surface
F	0015630	cellular_component	microtubule cytoskeleton
F	0016787	molecular_function	hydrolase activity
F	0019677	biological_process	NAD+ catabolic process
F	0030154	biological_process	cell differentiation
F	0030424	cellular_component	axon
F	0030425	cellular_component	dendrite
F	0031594	cellular_component	neuromuscular junction
F	0032991	cellular_component	protein-containing complex
F	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
F	0035591	molecular_function	signaling adaptor activity
F	0043068	biological_process	positive regulation of programmed cell death
F	0045087	biological_process	innate immune response
F	0045202	cellular_component	synapse
F	0048678	biological_process	response to axon injury
F	0048814	biological_process	regulation of dendrite morphogenesis
F	0050135	molecular_function	NADP+ nucleosidase activity
F	0050877	biological_process	nervous system process
F	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
F	0070585	biological_process	protein localization to mitochondrion
F	0098978	cellular_component	glutamatergic synapse
F	0099010	biological_process	modification of postsynaptic structure
F	0099243	cellular_component	extrinsic component of synaptic membrane
F	1905806	biological_process	regulation of synapse pruning
G	0002376	biological_process	immune system process
G	0003690	molecular_function	double-stranded DNA binding
G	0003953	molecular_function	NAD+ nucleosidase activity
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005741	cellular_component	mitochondrial outer membrane
G	0005829	cellular_component	cytosol
G	0005874	cellular_component	microtubule
G	0007165	biological_process	signal transduction
G	0007399	biological_process	nervous system development
G	0009986	cellular_component	cell surface
G	0015630	cellular_component	microtubule cytoskeleton
G	0016787	molecular_function	hydrolase activity
G	0019677	biological_process	NAD+ catabolic process
G	0030154	biological_process	cell differentiation
G	0030424	cellular_component	axon
G	0030425	cellular_component	dendrite
G	0031594	cellular_component	neuromuscular junction
G	0032991	cellular_component	protein-containing complex
G	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
G	0035591	molecular_function	signaling adaptor activity
G	0043068	biological_process	positive regulation of programmed cell death
G	0045087	biological_process	innate immune response
G	0045202	cellular_component	synapse
G	0048678	biological_process	response to axon injury
G	0048814	biological_process	regulation of dendrite morphogenesis
G	0050135	molecular_function	NADP+ nucleosidase activity
G	0050877	biological_process	nervous system process
G	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
G	0070585	biological_process	protein localization to mitochondrion
G	0098978	cellular_component	glutamatergic synapse
G	0099010	biological_process	modification of postsynaptic structure
G	0099243	cellular_component	extrinsic component of synaptic membrane
G	1905806	biological_process	regulation of synapse pruning
H	0002376	biological_process	immune system process
H	0003690	molecular_function	double-stranded DNA binding
H	0003953	molecular_function	NAD+ nucleosidase activity
H	0005515	molecular_function	protein binding
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005741	cellular_component	mitochondrial outer membrane
H	0005829	cellular_component	cytosol
H	0005874	cellular_component	microtubule
H	0007165	biological_process	signal transduction
H	0007399	biological_process	nervous system development
H	0009986	cellular_component	cell surface
H	0015630	cellular_component	microtubule cytoskeleton
H	0016787	molecular_function	hydrolase activity
H	0019677	biological_process	NAD+ catabolic process
H	0030154	biological_process	cell differentiation
H	0030424	cellular_component	axon
H	0030425	cellular_component	dendrite
H	0031594	cellular_component	neuromuscular junction
H	0032991	cellular_component	protein-containing complex
H	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
H	0035591	molecular_function	signaling adaptor activity
H	0043068	biological_process	positive regulation of programmed cell death
H	0045087	biological_process	innate immune response
H	0045202	cellular_component	synapse
H	0048678	biological_process	response to axon injury
H	0048814	biological_process	regulation of dendrite morphogenesis
H	0050135	molecular_function	NADP+ nucleosidase activity
H	0050877	biological_process	nervous system process
H	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
H	0070585	biological_process	protein localization to mitochondrion
H	0098978	cellular_component	glutamatergic synapse
H	0099010	biological_process	modification of postsynaptic structure
H	0099243	cellular_component	extrinsic component of synaptic membrane
H	1905806	biological_process	regulation of synapse pruning
I	0002376	biological_process	immune system process
I	0003690	molecular_function	double-stranded DNA binding
I	0003953	molecular_function	NAD+ nucleosidase activity
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005741	cellular_component	mitochondrial outer membrane
I	0005829	cellular_component	cytosol
I	0005874	cellular_component	microtubule
I	0007165	biological_process	signal transduction
I	0007399	biological_process	nervous system development
I	0009986	cellular_component	cell surface
I	0015630	cellular_component	microtubule cytoskeleton
I	0016787	molecular_function	hydrolase activity
I	0019677	biological_process	NAD+ catabolic process
I	0030154	biological_process	cell differentiation
I	0030424	cellular_component	axon
I	0030425	cellular_component	dendrite
I	0031594	cellular_component	neuromuscular junction
I	0032991	cellular_component	protein-containing complex
I	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
I	0035591	molecular_function	signaling adaptor activity
I	0043068	biological_process	positive regulation of programmed cell death
I	0045087	biological_process	innate immune response
I	0045202	cellular_component	synapse
I	0048678	biological_process	response to axon injury
I	0048814	biological_process	regulation of dendrite morphogenesis
I	0050135	molecular_function	NADP+ nucleosidase activity
I	0050877	biological_process	nervous system process
I	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
I	0070585	biological_process	protein localization to mitochondrion
I	0098978	cellular_component	glutamatergic synapse
I	0099010	biological_process	modification of postsynaptic structure
I	0099243	cellular_component	extrinsic component of synaptic membrane
I	1905806	biological_process	regulation of synapse pruning
J	0002376	biological_process	immune system process
J	0003690	molecular_function	double-stranded DNA binding
J	0003953	molecular_function	NAD+ nucleosidase activity
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005741	cellular_component	mitochondrial outer membrane
J	0005829	cellular_component	cytosol
J	0005874	cellular_component	microtubule
J	0007165	biological_process	signal transduction
J	0007399	biological_process	nervous system development
J	0009986	cellular_component	cell surface
J	0015630	cellular_component	microtubule cytoskeleton
J	0016787	molecular_function	hydrolase activity
J	0019677	biological_process	NAD+ catabolic process
J	0030154	biological_process	cell differentiation
J	0030424	cellular_component	axon
J	0030425	cellular_component	dendrite
J	0031594	cellular_component	neuromuscular junction
J	0032991	cellular_component	protein-containing complex
J	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
J	0035591	molecular_function	signaling adaptor activity
J	0043068	biological_process	positive regulation of programmed cell death
J	0045087	biological_process	innate immune response
J	0045202	cellular_component	synapse
J	0048678	biological_process	response to axon injury
J	0048814	biological_process	regulation of dendrite morphogenesis
J	0050135	molecular_function	NADP+ nucleosidase activity
J	0050877	biological_process	nervous system process
J	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
J	0070585	biological_process	protein localization to mitochondrion
J	0098978	cellular_component	glutamatergic synapse
J	0099010	biological_process	modification of postsynaptic structure
J	0099243	cellular_component	extrinsic component of synaptic membrane
J	1905806	biological_process	regulation of synapse pruning
K	0002376	biological_process	immune system process
K	0003690	molecular_function	double-stranded DNA binding
K	0003953	molecular_function	NAD+ nucleosidase activity
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005741	cellular_component	mitochondrial outer membrane
K	0005829	cellular_component	cytosol
K	0005874	cellular_component	microtubule
K	0007165	biological_process	signal transduction
K	0007399	biological_process	nervous system development
K	0009986	cellular_component	cell surface
K	0015630	cellular_component	microtubule cytoskeleton
K	0016787	molecular_function	hydrolase activity
K	0019677	biological_process	NAD+ catabolic process
K	0030154	biological_process	cell differentiation
K	0030424	cellular_component	axon
K	0030425	cellular_component	dendrite
K	0031594	cellular_component	neuromuscular junction
K	0032991	cellular_component	protein-containing complex
K	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
K	0035591	molecular_function	signaling adaptor activity
K	0043068	biological_process	positive regulation of programmed cell death
K	0045087	biological_process	innate immune response
K	0045202	cellular_component	synapse
K	0048678	biological_process	response to axon injury
K	0048814	biological_process	regulation of dendrite morphogenesis
K	0050135	molecular_function	NADP+ nucleosidase activity
K	0050877	biological_process	nervous system process
K	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
K	0070585	biological_process	protein localization to mitochondrion
K	0098978	cellular_component	glutamatergic synapse
K	0099010	biological_process	modification of postsynaptic structure
K	0099243	cellular_component	extrinsic component of synaptic membrane
K	1905806	biological_process	regulation of synapse pruning
L	0002376	biological_process	immune system process
L	0003690	molecular_function	double-stranded DNA binding
L	0003953	molecular_function	NAD+ nucleosidase activity
L	0005515	molecular_function	protein binding
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005741	cellular_component	mitochondrial outer membrane
L	0005829	cellular_component	cytosol
L	0005874	cellular_component	microtubule
L	0007165	biological_process	signal transduction
L	0007399	biological_process	nervous system development
L	0009986	cellular_component	cell surface
L	0015630	cellular_component	microtubule cytoskeleton
L	0016787	molecular_function	hydrolase activity
L	0019677	biological_process	NAD+ catabolic process
L	0030154	biological_process	cell differentiation
L	0030424	cellular_component	axon
L	0030425	cellular_component	dendrite
L	0031594	cellular_component	neuromuscular junction
L	0032991	cellular_component	protein-containing complex
L	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
L	0035591	molecular_function	signaling adaptor activity
L	0043068	biological_process	positive regulation of programmed cell death
L	0045087	biological_process	innate immune response
L	0045202	cellular_component	synapse
L	0048678	biological_process	response to axon injury
L	0048814	biological_process	regulation of dendrite morphogenesis
L	0050135	molecular_function	NADP+ nucleosidase activity
L	0050877	biological_process	nervous system process
L	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
L	0070585	biological_process	protein localization to mitochondrion
L	0098978	cellular_component	glutamatergic synapse
L	0099010	biological_process	modification of postsynaptic structure
L	0099243	cellular_component	extrinsic component of synaptic membrane
L	1905806	biological_process	regulation of synapse pruning
M	0002376	biological_process	immune system process
M	0003690	molecular_function	double-stranded DNA binding
M	0003953	molecular_function	NAD+ nucleosidase activity
M	0005515	molecular_function	protein binding
M	0005737	cellular_component	cytoplasm
M	0005739	cellular_component	mitochondrion
M	0005741	cellular_component	mitochondrial outer membrane
M	0005829	cellular_component	cytosol
M	0005874	cellular_component	microtubule
M	0007165	biological_process	signal transduction
M	0007399	biological_process	nervous system development
M	0009986	cellular_component	cell surface
M	0015630	cellular_component	microtubule cytoskeleton
M	0016787	molecular_function	hydrolase activity
M	0019677	biological_process	NAD+ catabolic process
M	0030154	biological_process	cell differentiation
M	0030424	cellular_component	axon
M	0030425	cellular_component	dendrite
M	0031594	cellular_component	neuromuscular junction
M	0032991	cellular_component	protein-containing complex
M	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
M	0035591	molecular_function	signaling adaptor activity
M	0043068	biological_process	positive regulation of programmed cell death
M	0045087	biological_process	innate immune response
M	0045202	cellular_component	synapse
M	0048678	biological_process	response to axon injury
M	0048814	biological_process	regulation of dendrite morphogenesis
M	0050135	molecular_function	NADP+ nucleosidase activity
M	0050877	biological_process	nervous system process
M	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
M	0070585	biological_process	protein localization to mitochondrion
M	0098978	cellular_component	glutamatergic synapse
M	0099010	biological_process	modification of postsynaptic structure
M	0099243	cellular_component	extrinsic component of synaptic membrane
M	1905806	biological_process	regulation of synapse pruning
N	0002376	biological_process	immune system process
N	0003690	molecular_function	double-stranded DNA binding
N	0003953	molecular_function	NAD+ nucleosidase activity
N	0005515	molecular_function	protein binding
N	0005737	cellular_component	cytoplasm
N	0005739	cellular_component	mitochondrion
N	0005741	cellular_component	mitochondrial outer membrane
N	0005829	cellular_component	cytosol
N	0005874	cellular_component	microtubule
N	0007165	biological_process	signal transduction
N	0007399	biological_process	nervous system development
N	0009986	cellular_component	cell surface
N	0015630	cellular_component	microtubule cytoskeleton
N	0016787	molecular_function	hydrolase activity
N	0019677	biological_process	NAD+ catabolic process
N	0030154	biological_process	cell differentiation
N	0030424	cellular_component	axon
N	0030425	cellular_component	dendrite
N	0031594	cellular_component	neuromuscular junction
N	0032991	cellular_component	protein-containing complex
N	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
N	0035591	molecular_function	signaling adaptor activity
N	0043068	biological_process	positive regulation of programmed cell death
N	0045087	biological_process	innate immune response
N	0045202	cellular_component	synapse
N	0048678	biological_process	response to axon injury
N	0048814	biological_process	regulation of dendrite morphogenesis
N	0050135	molecular_function	NADP+ nucleosidase activity
N	0050877	biological_process	nervous system process
N	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
N	0070585	biological_process	protein localization to mitochondrion
N	0098978	cellular_component	glutamatergic synapse
N	0099010	biological_process	modification of postsynaptic structure
N	0099243	cellular_component	extrinsic component of synaptic membrane
N	1905806	biological_process	regulation of synapse pruning
O	0002376	biological_process	immune system process
O	0003690	molecular_function	double-stranded DNA binding
O	0003953	molecular_function	NAD+ nucleosidase activity
O	0005515	molecular_function	protein binding
O	0005737	cellular_component	cytoplasm
O	0005739	cellular_component	mitochondrion
O	0005741	cellular_component	mitochondrial outer membrane
O	0005829	cellular_component	cytosol
O	0005874	cellular_component	microtubule
O	0007165	biological_process	signal transduction
O	0007399	biological_process	nervous system development
O	0009986	cellular_component	cell surface
O	0015630	cellular_component	microtubule cytoskeleton
O	0016787	molecular_function	hydrolase activity
O	0019677	biological_process	NAD+ catabolic process
O	0030154	biological_process	cell differentiation
O	0030424	cellular_component	axon
O	0030425	cellular_component	dendrite
O	0031594	cellular_component	neuromuscular junction
O	0032991	cellular_component	protein-containing complex
O	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
O	0035591	molecular_function	signaling adaptor activity
O	0043068	biological_process	positive regulation of programmed cell death
O	0045087	biological_process	innate immune response
O	0045202	cellular_component	synapse
O	0048678	biological_process	response to axon injury
O	0048814	biological_process	regulation of dendrite morphogenesis
O	0050135	molecular_function	NADP+ nucleosidase activity
O	0050877	biological_process	nervous system process
O	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
O	0070585	biological_process	protein localization to mitochondrion
O	0098978	cellular_component	glutamatergic synapse
O	0099010	biological_process	modification of postsynaptic structure
O	0099243	cellular_component	extrinsic component of synaptic membrane
O	1905806	biological_process	regulation of synapse pruning
P	0002376	biological_process	immune system process
P	0003690	molecular_function	double-stranded DNA binding
P	0003953	molecular_function	NAD+ nucleosidase activity
P	0005515	molecular_function	protein binding
P	0005737	cellular_component	cytoplasm
P	0005739	cellular_component	mitochondrion
P	0005741	cellular_component	mitochondrial outer membrane
P	0005829	cellular_component	cytosol
P	0005874	cellular_component	microtubule
P	0007165	biological_process	signal transduction
P	0007399	biological_process	nervous system development
P	0009986	cellular_component	cell surface
P	0015630	cellular_component	microtubule cytoskeleton
P	0016787	molecular_function	hydrolase activity
P	0019677	biological_process	NAD+ catabolic process
P	0030154	biological_process	cell differentiation
P	0030424	cellular_component	axon
P	0030425	cellular_component	dendrite
P	0031594	cellular_component	neuromuscular junction
P	0032991	cellular_component	protein-containing complex
P	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
P	0035591	molecular_function	signaling adaptor activity
P	0043068	biological_process	positive regulation of programmed cell death
P	0045087	biological_process	innate immune response
P	0045202	cellular_component	synapse
P	0048678	biological_process	response to axon injury
P	0048814	biological_process	regulation of dendrite morphogenesis
P	0050135	molecular_function	NADP+ nucleosidase activity
P	0050877	biological_process	nervous system process
P	0061809	molecular_function	NAD+ nucleosidase activity, cyclic ADP-ribose generating
P	0070585	biological_process	protein localization to mitochondrion
P	0098978	cellular_component	glutamatergic synapse
P	0099010	biological_process	modification of postsynaptic structure
P	0099243	cellular_component	extrinsic component of synaptic membrane
P	1905806	biological_process	regulation of synapse pruning

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	640
Details	Repeat: {"description":"ARM 1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	624
Details	Repeat: {"description":"ARM 2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	608
Details	Repeat: {"description":"ARM 3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	624
Details	Repeat: {"description":"ARM 4","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	688
Details	Repeat: {"description":"ARM 5","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	688
Details	Repeat: {"description":"ARM 8","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1024
Details	Domain: {"description":"SAM 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00184","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	992
Details	Domain: {"description":"SAM 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00184","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	16
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00204","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"28334607","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"31439792","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"31439793","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	208
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33053563","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CM6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CM7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PubMed","id":"31439792","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	16
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"30333228","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---