7QG0

Inhibitor-induced hSARM1 duplex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	NAD(+) hydrolase SARM1	polymer	726	79971.3	16	UniProt (Q6SZW1) Pfam (PF07647) Pfam (PF13676)	Homo sapiens (Human)	hSARM1,NADP(+) hydrolase SARM1,Sterile alpha and Armadillo repeat protein,Sterile alpha and TIR motif-containing protein 1,Sterile alpha motif domain-containing protein 2,SAM domain-containing protein 2,Tir-1 homolog,HsTIR

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P: 26 - 724 (UniProt: Q6SZW1)

PDB	External Database	Details
Met -1	-	initiating methionine
Ser 0	-	expression tag
Tyr 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
Asp 8	-	expression tag
Tyr 9	-	expression tag
Asp 10	-	expression tag
Ile 11	-	expression tag
Pro 12	-	expression tag
Thr 13	-	expression tag
Thr 14	-	expression tag
Glu 15	-	expression tag
Asn 16	-	expression tag
Leu 17	-	expression tag
Tyr 18	-	expression tag
Phe 19	-	expression tag
Gln 20	-	expression tag
Gly 21	-	expression tag
Ala 22	-	expression tag
Met 23	-	expression tag
Gly 24	-	expression tag
Ser 25	-	expression tag
Gln 642	Glu 642	conflict

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	1279540.1
All*	Total formula weight	1279540.1

*Water molecules are not included.