8TDV

ssRNA bound SAMHD1 T closed

Summary for 8TDV

• Entry DOI: 10.2210/pdb8tdv/pdb
• EMDB information: 41174
• Descriptor: Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, RNA (5'-R(P*CP*CP*GP*GP*CP*C)-3'), RNA (5'-R(P*CP*CP*GP*AP*CP*CP*C)-3'), ... (4 entities in total)
• Functional Keywords: deoxynucleoside triphosphate triphosphohydrolase, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 293354.89

Authors

Sung, M.,Huynh, K.,Han, S. (deposition date: 2023-07-05, release date: 2023-12-20)

• Primary citation: Orris, B.,Sung, M.W.,Bhat, S.,Xu, Y.,Huynh, K.W.,Han, S.,Johnson, D.C.,Bosbach, B.,Shields, D.J.,Stivers, J.T.; Guanine-containing ssDNA and RNA induce dimeric and tetrameric structural forms of SAMHD1.; Nucleic Acids Res., 51:12443-12458, 2023; PubMed: 37930833; DOI: 10.1093/nar/gkad971

Experimental method

ELECTRON MICROSCOPY (3.44 Å)