8GNI
Human SARM1 bounded with NMN and Nanobody-C6, Conformation 1
Summary for 8GNI
Entry DOI | 10.2210/pdb8gni/pdb |
EMDB information | 34162 34165 |
Descriptor | NAD(+) hydrolase SARM1, Nanobody C6, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE (3 entities in total) |
Functional Keywords | nad(+)hydrolase, nmn, nanobody, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 172476.31 |
Authors | |
Primary citation | Hou, Y.N.,Cai, Y.,Li, W.H.,He, W.M.,Zhao, Z.Y.,Zhu, W.J.,Wang, Q.,Mai, X.,Liu, J.,Lee, H.C.,Stjepanovic, G.,Zhang, H.,Zhao, Y.J. A conformation-specific nanobody targeting the nicotinamide mononucleotide-activated state of SARM1. Nat Commun, 13:7898-7898, 2022 Cited by PubMed: 36550129DOI: 10.1038/s41467-022-35581-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.74 Å) |
Structure validation
Download full validation report