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8DS8
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BU of 8ds8 by Molmil
Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide
分子名称: Histone H3.1, Trinucleotide repeat-containing gene 18 protein
著者Song, J.K, Lu, J.W.
登録日2022-07-21
公開日2023-08-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons.
Nature, 623, 2023
6PZV
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BU of 6pzv by Molmil
Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin
分子名称: CITRATE ANION, DNA (cytosine-5)-methyltransferase 1, Histone H3.3, ...
著者Ren, W, Song, J.
登録日2019-08-01
公開日2020-07-15
最終更新日2020-08-12
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
4GY5
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BU of 4gy5 by Molmil
Crystal structure of the tandem tudor domain and plant homeodomain of UHRF1 with Histone H3K9me3
分子名称: E3 ubiquitin-protein ligase UHRF1, Peptide from Histone H3.3, ZINC ION
著者Cheng, J, Yang, Y, Fang, J, Xiao, J, Zhu, T, Chen, F, Wang, P, Xu, Y.
登録日2012-09-05
公開日2012-11-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.956 Å)
主引用文献Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein
J.Biol.Chem., 288, 2013
7VRF
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BU of 7vrf by Molmil
Crystal structure of Oxpecker chromodomain in complex with H3K9me3
分子名称: H3K9me3, Oxpecker
著者Huang, Y, Jin, Z, Yu, B.
登録日2021-10-22
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insights into the chromodomain of Oxpecker in complex with histone H3 lysine 9 trimethylation reveal a transposon silencing mechanism by heterodimerization.
Biochem.Biophys.Res.Commun., 652, 2023
9BAQ
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BU of 9baq by Molmil
CryoEM structure of DIM2-HP1-H3K9me3-DNA complex
分子名称: DNA (5'-D(*AP*CP*TP*AP*CP*T)-R(P*(PYO))-D(P*CP*TP*CP*CP*TP*CP*CP*TP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*TP*AP*GP*T)-3'), DNA (cytosine-5-)-methyltransferase, ...
著者Song, J, Shao, Z.
登録日2024-04-04
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献CryoEM structure of DIM2-HP1-H3K9me3-DNA complex
To Be Published
4LXL
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BU of 4lxl by Molmil
Crystal structure of JMJD2B complexed with pyridine-2,4-dicarboxylic acid and H3K9me3
分子名称: H3 peptide, Lysine-specific demethylase 4B, NICKEL (II) ION, ...
著者Wang, W.-C, Chu, C.-H, Chen, C.-C.
登録日2013-07-30
公開日2014-07-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structure of JMJD2B complexed with pyridine-2,4-dicarboxylic acid and H3K9me3
To be Published
5XPI
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BU of 5xpi by Molmil
Structure of UHRF1 TTD in complex with NV01
分子名称: E3 ubiquitin-protein ligase UHRF1, N-[3-(diethylamino)propyl]-2-(12-methyl-9-oxidanylidene-5-thia-1,10,11-triazatricyclo[6.4.0.0^2,6]dodeca-2(6),3,7,11-tetraen-10-yl)ethanamide
著者Luo, X, Zhao, K.
登録日2017-06-02
公開日2018-04-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain
SLAS Discov, 23, 2018
4U68
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BU of 4u68 by Molmil
Crystal structure of Rhino chromodomain in complex with H3K9me3
分子名称: H3K9me3, Rhino
著者Yu, B.W, Huang, Y.
登録日2014-07-28
公開日2015-08-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into Rhino-mediated germline piRNA cluster formation
Cell Res., 25, 2015
3R93
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BU of 3r93 by Molmil
Crystal structure of the chromo domain of M-phase phosphoprotein 8 bound to H3K9Me3 peptide
分子名称: H3K9Me3 peptide, M-phase phosphoprotein 8, UNKNOWN ATOM OR ION
著者Li, J, Li, Z, Ruan, J, Xu, C, Tong, Y, Pan, P.W, Tempel, W, Crombet, L, Min, J, Zang, J, Structural Genomics Consortium (SGC)
登録日2011-03-24
公開日2011-04-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.057 Å)
主引用文献Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
4YHP
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BU of 4yhp by Molmil
Crystal structure of 309M3-B Fab in complex with H3K9me3 peptide
分子名称: Fab Heavy Chain, Fab Light Chain, H3K9me3 peptide
著者Hattori, T, Dementieva, I.S, Montano, S.P, Koide, S.
登録日2015-02-27
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation.
Proc.Natl.Acad.Sci.USA, 113, 2016
4HON
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BU of 4hon by Molmil
Crystal structure of human JMJD2D/KDM4D in complex with an H3K9me3 peptide and 2-oxoglutarate
分子名称: 1,3-PROPANDIOL, 2-OXOGLUTARIC ACID, Histone H3 Peptide, ...
著者Krishnan, S, Trievel, R.C.
登録日2012-10-22
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases.
Structure, 21, 2013
2L12
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BU of 2l12 by Molmil
Solution NMR structure of the chromobox protein 7 with H3K9me3
分子名称: Chromobox homolog 7, Histone H3
著者Kaustov, L, Lemak, A, Gutmanas, A, Fares, C, Quang, H, Loppnau, P, Min, J, Edwards, A, Arrowsmith, C, Structural Genomics Consortium (SGC)
登録日2010-07-22
公開日2010-08-04
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
3QL9
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BU of 3ql9 by Molmil
Monoclinic complex structure of ATRX ADD bound to histone H3K9me3 peptide
分子名称: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3
著者Xiang, B, Li, H.
登録日2011-02-02
公開日2011-06-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (0.93 Å)
主引用文献ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
3QLA
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BU of 3qla by Molmil
Hexagonal complex structure of ATRX ADD bound to H3K9me3 peptide
分子名称: POTASSIUM ION, Transcriptional regulator ATRX, ZINC ION, ...
著者Xiang, B, Li, H.
登録日2011-02-02
公開日2011-06-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011
2L75
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BU of 2l75 by Molmil
Solution structure of CHD4-PHD2 in complex with H3K9me3
分子名称: 14-meric peptide from 1Histone H3.1, Chromodomain-helicase-DNA-binding protein 4, ZINC ION
著者Mansfield, R.E, Kwan, A.H, Mackay, J.P.
登録日2010-12-02
公開日2011-01-19
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Plant Homeodomain (PHD) Fingers of CHD4 Are Histone H3-binding Modules with Preference for Unmodified H3K4 and Methylated H3K9
J.Biol.Chem., 286, 2011
4QUF
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BU of 4quf by Molmil
crystal structure of chromodomain of Rhino with H3K9me3
分子名称: H3(1-15)K9me3 peptide, RE36324p
著者Li, S, Patel, D.J.
登録日2014-07-10
公開日2014-08-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing.
Genes Dev., 28, 2014
4GNG
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BU of 4gng by Molmil
Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3K9me3 peptide
分子名称: GLYCEROL, Histone H3.3, Histone-lysine N-methyltransferase NSD3, ...
著者Li, F, He, C, Wu, J, Shi, Y.
登録日2012-08-17
公開日2013-01-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition.
J.Biol.Chem., 288, 2013
2L11
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BU of 2l11 by Molmil
Solution NMR structure of the Cbx3 in complex with H3K9me3 peptide
分子名称: Chromobox protein homolog 3, Histone H3
著者Kaustov, L, Lemak, A, Fares, C, Gutmanas, A, Quang, H, Loppnau, P, Min, J, Edwards, A, Arrowsmith, C, Structural Genomics Consortium (SGC)
登録日2010-07-22
公開日2010-08-04
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
3GV6
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BU of 3gv6 by Molmil
Crystal Structure of human chromobox homolog 6 (CBX6) with H3K9 peptide
分子名称: Chromobox protein homolog 6, Histone H3K9me3 peptide
著者Dong, A, Amaya, M.F, Li, Z, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
登録日2009-03-30
公開日2009-04-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
6V41
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BU of 6v41 by Molmil
crystal structure of CDY1 chromodomain bound to H3K9me3
分子名称: Histone H3.1 Peptide, Testis-specific chromodomain protein Y 1, UNKNOWN ATOM OR ION
著者Qin, S, Tempel, W, Walker, J.R, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
登録日2019-11-27
公開日2019-12-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.603 Å)
主引用文献Structural Basis for the Binding Selectivity of Human CDY Chromodomains.
Cell Chem Biol, 27, 2020
2Q8C
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BU of 2q8c by Molmil
Crystal structure of JMJD2A in ternary complex with an histone H3K9me3 peptide and 2-oxoglutarate
分子名称: 2-OXOGLUTARIC ACID, HISTONE 3 PEPTIDE, JmjC domain-containing histone demethylation protein 3A, ...
著者Couture, J.-F, Collazo, E, Ortiz-Tello, P, Brunzelle, J.S, Trievel, R.C.
登録日2007-06-10
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.047 Å)
主引用文献Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.
Nat.Struct.Mol.Biol., 14, 2007
4W5A
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BU of 4w5a by Molmil
Complex structure of ATRX ADD bound to H3K9me3S10ph peptide
分子名称: Peptide from Histone H3.3, Transcriptional regulator ATRX, ZINC ION
著者Zhao, D, Xiang, B, Li, H.
登録日2014-08-17
公開日2015-01-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons
Proc.Natl.Acad.Sci.USA, 112, 2015
7EBK
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BU of 7ebk by Molmil
Mouse Trim66 PHD-Bromo dual domain complexed with the H3(1-24)K9me3K18ac peptide
分子名称: H3K9me3K18ac, Tripartite motif-containing protein 66, ZINC ION
著者Wang, Z, Jiang, J.
登録日2021-03-09
公開日2022-03-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献A TRIM66/DAX1/Dux axis suppresses the totipotent 2-cell-like state in murine embryonic stem cells.
Cell Stem Cell, 29, 2022
2RSN
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BU of 2rsn by Molmil
Solution structure of the chromodomain of Chp1 in complex with H3K9me3 peptide
分子名称: Chromo domain-containing protein 1, peptide from Histone H3
著者Shimojo, H, Nishimura, Y.
登録日2012-04-18
公開日2012-08-29
実験手法SOLUTION NMR
主引用文献Intrinsic nucleic Acid-binding activity of chp1 chromodomain is required for heterochromatic gene silencing
Mol.Cell, 47, 2012
3QLC
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BU of 3qlc by Molmil
Complex structure of ATRX ADD domain bound to unmodified H3 1-15 peptide
分子名称: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3
著者Li, H, Patel, D.J.
登録日2011-02-02
公開日2011-06-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome
Nat.Struct.Mol.Biol., 18, 2011

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件を2024-09-18に公開中

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