PDB: 118 件ウェブページステータス検索Chemie searchBIRD

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8DS8	Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide 分子名称: Histone H3.1, Trinucleotide repeat-containing gene 18 protein 著者 Song, J.K, Lu, J.W. 登録日 2022-07-21 公開日 2023-08-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons. Nature, 623, 2023
6PZV	Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin 分子名称: CITRATE ANION, DNA (cytosine-5)-methyltransferase 1, Histone H3.3, ... 著者 Ren, W, Song, J. 登録日 2019-08-01 公開日 2020-07-15 最終更新日 2020-08-12 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation. Proc.Natl.Acad.Sci.USA, 117, 2020
4GY5	Crystal structure of the tandem tudor domain and plant homeodomain of UHRF1 with Histone H3K9me3 分子名称: E3 ubiquitin-protein ligase UHRF1, Peptide from Histone H3.3, ZINC ION 著者 Cheng, J, Yang, Y, Fang, J, Xiao, J, Zhu, T, Chen, F, Wang, P, Xu, Y. 登録日 2012-09-05 公開日 2012-11-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.956 Å) 主引用文献 Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein J.Biol.Chem., 288, 2013
7VRF	Crystal structure of Oxpecker chromodomain in complex with H3K9me3 分子名称: H3K9me3, Oxpecker 著者 Huang, Y, Jin, Z, Yu, B. 登録日 2021-10-22 公開日 2022-10-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural insights into the chromodomain of Oxpecker in complex with histone H3 lysine 9 trimethylation reveal a transposon silencing mechanism by heterodimerization. Biochem.Biophys.Res.Commun., 652, 2023
9BAQ	CryoEM structure of DIM2-HP1-H3K9me3-DNA complex 分子名称: DNA (5'-D(*AP*CP*TP*AP*CP*T)-R(P*(PYO))-D(P*CP*TP*CP*CP*TP*CP*CP*TP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*AP*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*TP*AP*GP*T)-3'), DNA (cytosine-5-)-methyltransferase, ... 著者 Song, J, Shao, Z. 登録日 2024-04-04 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.79 Å) 主引用文献 CryoEM structure of DIM2-HP1-H3K9me3-DNA complex To Be Published
4LXL	Crystal structure of JMJD2B complexed with pyridine-2,4-dicarboxylic acid and H3K9me3 分子名称: H3 peptide, Lysine-specific demethylase 4B, NICKEL (II) ION, ... 著者 Wang, W.-C, Chu, C.-H, Chen, C.-C. 登録日 2013-07-30 公開日 2014-07-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Crystal structure of JMJD2B complexed with pyridine-2,4-dicarboxylic acid and H3K9me3 To be Published
5XPI	Structure of UHRF1 TTD in complex with NV01 分子名称: E3 ubiquitin-protein ligase UHRF1, N-[3-(diethylamino)propyl]-2-(12-methyl-9-oxidanylidene-5-thia-1,10,11-triazatricyclo[6.4.0.0^2,6]dodeca-2(6),3,7,11-tetraen-10-yl)ethanamide 著者 Luo, X, Zhao, K. 登録日 2017-06-02 公開日 2018-04-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain SLAS Discov, 23, 2018
4U68	Crystal structure of Rhino chromodomain in complex with H3K9me3 分子名称: H3K9me3, Rhino 著者 Yu, B.W, Huang, Y. 登録日 2014-07-28 公開日 2015-08-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural insights into Rhino-mediated germline piRNA cluster formation Cell Res., 25, 2015
3R93	Crystal structure of the chromo domain of M-phase phosphoprotein 8 bound to H3K9Me3 peptide 分子名称: H3K9Me3 peptide, M-phase phosphoprotein 8, UNKNOWN ATOM OR ION 著者 Li, J, Li, Z, Ruan, J, Xu, C, Tong, Y, Pan, P.W, Tempel, W, Crombet, L, Min, J, Zang, J, Structural Genomics Consortium (SGC) 登録日 2011-03-24 公開日 2011-04-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.057 Å) 主引用文献 Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9. Plos One, 6, 2011
4YHP	Crystal structure of 309M3-B Fab in complex with H3K9me3 peptide 分子名称: Fab Heavy Chain, Fab Light Chain, H3K9me3 peptide 著者 Hattori, T, Dementieva, I.S, Montano, S.P, Koide, S. 登録日 2015-02-27 公開日 2016-02-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation. Proc.Natl.Acad.Sci.USA, 113, 2016
4HON	Crystal structure of human JMJD2D/KDM4D in complex with an H3K9me3 peptide and 2-oxoglutarate 分子名称: 1,3-PROPANDIOL, 2-OXOGLUTARIC ACID, Histone H3 Peptide, ... 著者 Krishnan, S, Trievel, R.C. 登録日 2012-10-22 公開日 2012-11-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases. Structure, 21, 2013
2L12	Solution NMR structure of the chromobox protein 7 with H3K9me3 分子名称: Chromobox homolog 7, Histone H3 著者 Kaustov, L, Lemak, A, Gutmanas, A, Fares, C, Quang, H, Loppnau, P, Min, J, Edwards, A, Arrowsmith, C, Structural Genomics Consortium (SGC) 登録日 2010-07-22 公開日 2010-08-04 最終更新日 2020-02-05 実験手法 SOLUTION NMR 主引用文献 Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
3QL9	Monoclinic complex structure of ATRX ADD bound to histone H3K9me3 peptide 分子名称: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3 著者 Xiang, B, Li, H. 登録日 2011-02-02 公開日 2011-06-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (0.93 Å) 主引用文献 ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome Nat.Struct.Mol.Biol., 18, 2011
3QLA	Hexagonal complex structure of ATRX ADD bound to H3K9me3 peptide 分子名称: POTASSIUM ION, Transcriptional regulator ATRX, ZINC ION, ... 著者 Xiang, B, Li, H. 登録日 2011-02-02 公開日 2011-06-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome Nat.Struct.Mol.Biol., 18, 2011
2L75	Solution structure of CHD4-PHD2 in complex with H3K9me3 分子名称: 14-meric peptide from 1Histone H3.1, Chromodomain-helicase-DNA-binding protein 4, ZINC ION 著者 Mansfield, R.E, Kwan, A.H, Mackay, J.P. 登録日 2010-12-02 公開日 2011-01-19 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Plant Homeodomain (PHD) Fingers of CHD4 Are Histone H3-binding Modules with Preference for Unmodified H3K4 and Methylated H3K9 J.Biol.Chem., 286, 2011
4QUF	crystal structure of chromodomain of Rhino with H3K9me3 分子名称: H3(1-15)K9me3 peptide, RE36324p 著者 Li, S, Patel, D.J. 登録日 2014-07-10 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing. Genes Dev., 28, 2014
4GNG	Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3K9me3 peptide 分子名称: GLYCEROL, Histone H3.3, Histone-lysine N-methyltransferase NSD3, ... 著者 Li, F, He, C, Wu, J, Shi, Y. 登録日 2012-08-17 公開日 2013-01-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition. J.Biol.Chem., 288, 2013
2L11	Solution NMR structure of the Cbx3 in complex with H3K9me3 peptide 分子名称: Chromobox protein homolog 3, Histone H3 著者 Kaustov, L, Lemak, A, Fares, C, Gutmanas, A, Quang, H, Loppnau, P, Min, J, Edwards, A, Arrowsmith, C, Structural Genomics Consortium (SGC) 登録日 2010-07-22 公開日 2010-08-04 最終更新日 2020-02-05 実験手法 SOLUTION NMR 主引用文献 Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
3GV6	Crystal Structure of human chromobox homolog 6 (CBX6) with H3K9 peptide 分子名称: Chromobox protein homolog 6, Histone H3K9me3 peptide 著者 Dong, A, Amaya, M.F, Li, Z, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) 登録日 2009-03-30 公開日 2009-04-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
6V41	crystal structure of CDY1 chromodomain bound to H3K9me3 分子名称: Histone H3.1 Peptide, Testis-specific chromodomain protein Y 1, UNKNOWN ATOM OR ION 著者 Qin, S, Tempel, W, Walker, J.R, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC) 登録日 2019-11-27 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.603 Å) 主引用文献 Structural Basis for the Binding Selectivity of Human CDY Chromodomains. Cell Chem Biol, 27, 2020
2Q8C	Crystal structure of JMJD2A in ternary complex with an histone H3K9me3 peptide and 2-oxoglutarate 分子名称: 2-OXOGLUTARIC ACID, HISTONE 3 PEPTIDE, JmjC domain-containing histone demethylation protein 3A, ... 著者 Couture, J.-F, Collazo, E, Ortiz-Tello, P, Brunzelle, J.S, Trievel, R.C. 登録日 2007-06-10 公開日 2007-07-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.047 Å) 主引用文献 Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase. Nat.Struct.Mol.Biol., 14, 2007
4W5A	Complex structure of ATRX ADD bound to H3K9me3S10ph peptide 分子名称: Peptide from Histone H3.3, Transcriptional regulator ATRX, ZINC ION 著者 Zhao, D, Xiang, B, Li, H. 登録日 2014-08-17 公開日 2015-01-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons Proc.Natl.Acad.Sci.USA, 112, 2015
7EBK	Mouse Trim66 PHD-Bromo dual domain complexed with the H3(1-24)K9me3K18ac peptide 分子名称: H3K9me3K18ac, Tripartite motif-containing protein 66, ZINC ION 著者 Wang, Z, Jiang, J. 登録日 2021-03-09 公開日 2022-03-09 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 A TRIM66/DAX1/Dux axis suppresses the totipotent 2-cell-like state in murine embryonic stem cells. Cell Stem Cell, 29, 2022
2RSN	Solution structure of the chromodomain of Chp1 in complex with H3K9me3 peptide 分子名称: Chromo domain-containing protein 1, peptide from Histone H3 著者 Shimojo, H, Nishimura, Y. 登録日 2012-04-18 公開日 2012-08-29 実験手法 SOLUTION NMR 主引用文献 Intrinsic nucleic Acid-binding activity of chp1 chromodomain is required for heterochromatic gene silencing Mol.Cell, 47, 2012
3QLC	Complex structure of ATRX ADD domain bound to unmodified H3 1-15 peptide 分子名称: Transcriptional regulator ATRX, ZINC ION, peptide of Histone H3.3 著者 Li, H, Patel, D.J. 登録日 2011-02-02 公開日 2011-06-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome Nat.Struct.Mol.Biol., 18, 2011

 

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