8DS8

Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide

Summary for 8DS8

Entry DOI	10.2210/pdb8ds8/pdb
Descriptor	Trinucleotide repeat-containing gene 18 protein, Histone H3.1 (3 entities in total)
Functional Keywords	protein complex, structural protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	47931.10
Authors	Song, J.K.,Lu, J.W. (deposition date: 2022-07-21, release date: 2023-08-02, Last modification date: 2023-11-29)
Primary citation	Zhao, S.,Lu, J.,Pan, B.,Fan, H.,Byrum, S.D.,Xu, C.,Kim, A.,Guo, Y.,Kanchi, K.L.,Gong, W.,Sun, T.,Storey, A.J.,Burkholder, N.T.,Mackintosh, S.G.,Kuhlers, P.C.,Edmondson, R.D.,Strahl, B.D.,Diao, Y.,Tackett, A.J.,Raab, J.R.,Cai, L.,Song, J.,Wang, G.G. TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons. Nature, 623:633-642, 2023 Cited by PubMed: 37938770 DOI: 10.1038/s41586-023-06688-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.84 Å)

Structure validation