2Q8C
Crystal structure of JMJD2A in ternary complex with an histone H3K9me3 peptide and 2-oxoglutarate
Summary for 2Q8C
Entry DOI | 10.2210/pdb2q8c/pdb |
Related | 2Q8D 2Q8E |
Descriptor | JmjC domain-containing histone demethylation protein 3A, HISTONE 3 PEPTIDE, NICKEL (II) ION, ... (6 entities in total) |
Functional Keywords | histone demethylase, hydroxylase, jumonji, oxidoreductase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : O75164 |
Total number of polymer chains | 4 |
Total formula weight | 85483.16 |
Authors | Couture, J.-F.,Collazo, E.,Ortiz-Tello, P.,Brunzelle, J.S.,Trievel, R.C. (deposition date: 2007-06-10, release date: 2007-07-03, Last modification date: 2023-08-30) |
Primary citation | Couture, J.F.,Collazo, E.,Ortiz-Tello, P.A.,Brunzelle, J.S.,Trievel, R.C. Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase. Nat.Struct.Mol.Biol., 14:689-695, 2007 Cited by PubMed: 17589523DOI: 10.1038/nsmb1273 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.047 Å) |
Structure validation
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