2Q8C
Crystal structure of JMJD2A in ternary complex with an histone H3K9me3 peptide and 2-oxoglutarate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | JmjC domain-containing histone demethylation protein 3A | polymer | 352 | 40863.5 | 2 | UniProt (O75164) Pfam (PF02375) Pfam (PF02373) | Homo sapiens (human) | Jumonji domain-containing protein 2A |
| 2 | C, D (F, G) | HISTONE 3 PEPTIDE | polymer | 15 | 1607.9 | 2 | |||
| 3 | E, H (A, B) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 4 | F, I (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | G, J (A, B) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 2 | Chemie (AKG) | |||
| 6 | K, L, M (A, B, F) | water | water | 18.0 | 199 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 350 (UniProt: O75164)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
| Ser 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 84942.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 540.4 | |
| All* | Total formula weight | 85483.2 |
