Crystal Structure of human chromobox homolog 6 (CBX6) with H3K9 peptide

Summary for 3GV6

DescriptorChromobox protein homolog 6, Histone H3K9me3 peptide (3 entities in total)
Functional Keywordschromobox homolog, cbx6, h3k9 peptide, sgc, chromatin regulator, nucleus, phosphoprotein, repressor, transcription, transcription regulation, chromosomal protein, dna-binding, nucleosome core, transcription-dna binding protein complex, structural genomics, structural genomics consortium, transcription/dna binding protein
Biological sourceHomo sapiens (Human)
Cellular locationNucleus (By similarity) O95503
Total number of polymer chains2
Total molecular weight8745.08
Primary citation
Kaustov, L.,Ouyang, H.,Amaya, M.,Lemak, A.,Nady, N.,Duan, S.,Wasney, G.A.,Li, Z.,Vedadi, M.,Schapira, M.,Min, J.,Arrowsmith, C.H.
Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286:521-529, 2011
PubMed: 21047797 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M110.191411
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.255100 8.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28