4GY5
Crystal structure of the tandem tudor domain and plant homeodomain of UHRF1 with Histone H3K9me3
Summary for 4GY5
Entry DOI | 10.2210/pdb4gy5/pdb |
Descriptor | E3 ubiquitin-protein ligase UHRF1, Peptide from Histone H3.3, ZINC ION, ... (4 entities in total) |
Functional Keywords | histone binding, ligase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q96T88 P84243 |
Total number of polymer chains | 6 |
Total formula weight | 115359.35 |
Authors | |
Primary citation | Cheng, J.,Yang, Y.,Fang, J.,Xiao, J.,Zhu, T.,Chen, F.,Wang, P.,Li, Z.,Yang, H.,Xu, Y. Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein J.Biol.Chem., 288:1329-1339, 2013 Cited by PubMed: 23161542DOI: 10.1074/jbc.M112.415398 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.956 Å) |
Structure validation
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