4GNG
Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3K9me3 peptide
Summary for 4GNG
Entry DOI | 10.2210/pdb4gng/pdb |
Related | 4GND 4GNE 4GNF |
Descriptor | Histone-lysine N-methyltransferase NSD3, Histone H3.3, ZINC ION, ... (5 entities in total) |
Functional Keywords | zinc finger, transcription, histone, lysine methyaltion, nuclear protein, transferase-nuclear protein complex, transferase/nuclear protein |
Biological source | Homo sapiens More |
Cellular location | Nucleus (By similarity): Q9BZ95 Nucleus: P84243 |
Total number of polymer chains | 4 |
Total formula weight | 28132.89 |
Authors | |
Primary citation | He, C.,Li, F.,Zhang, J.,Wu, J.,Shi, Y. The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition. J.Biol.Chem., 288:4692-4703, 2013 Cited by PubMed: 23269674DOI: 10.1074/jbc.M112.426148 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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