4HON

Crystal structure of human JMJD2D/KDM4D in complex with an H3K9me3 peptide and 2-oxoglutarate

Summary for 4HON

Entry DOI	10.2210/pdb4hon/pdb
Descriptor	Lysine-specific demethylase 4D, Histone H3 Peptide, 2-OXOGLUTARIC ACID, ... (9 entities in total)
Functional Keywords	jumonji c demethylase, jmjd2/kdm4 family, beta barrel fold, oxidoreductase
Biological source	Homo sapiens (human) More
Cellular location	Nucleus : Q6B0I6
Total number of polymer chains	4
Total formula weight	80330.14
Authors	Krishnan, S.,Trievel, R.C. (deposition date: 2012-10-22, release date: 2012-11-21, Last modification date: 2023-09-20)
Primary citation	Krishnan, S.,Trievel, R.C. Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases. Structure, 21:98-108, 2013 Cited by PubMed: 23219879 DOI: 10.1016/j.str.2012.10.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.799 Å)

Structure validation