4YHP
Crystal structure of 309M3-B Fab in complex with H3K9me3 peptide
Summary for 4YHP
Entry DOI | 10.2210/pdb4yhp/pdb |
Related | 4YHP 4YHZ |
Descriptor | H3K9me3 peptide, Fab Heavy Chain, Fab Light Chain, ... (4 entities in total) |
Functional Keywords | antibody, fab, head-to-head dimerization, h3k9me3, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 10 |
Total formula weight | 195171.11 |
Authors | Hattori, T.,Dementieva, I.S.,Montano, S.P.,Koide, S. (deposition date: 2015-02-27, release date: 2016-02-10, Last modification date: 2023-09-27) |
Primary citation | Hattori, T.,Lai, D.,Dementieva, I.S.,Montano, S.P.,Kurosawa, K.,Zheng, Y.,Akin, L.R.,Swist-Rosowska, K.M.,Grzybowski, A.T.,Koide, A.,Krajewski, K.,Strahl, B.D.,Kelleher, N.L.,Ruthenburg, A.J.,Koide, S. Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation. Proc.Natl.Acad.Sci.USA, 113:2092-2097, 2016 Cited by PubMed: 26862167DOI: 10.1073/pnas.1522691113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.53 Å) |
Structure validation
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