7LQT
 
 | | Solution NMR structure of the PNUTS amino-terminal Domain fused to Myc Homology Box 0 | | Descriptor: | Serine/threonine-protein phosphatase 1 regulatory subunit 10,Myc proto-oncogene protein fusion | | Authors: | Lemak, A, Wei, Y, Duan, S, Houliston, S, Penn, L.Z, Arrowsmith, C.H. | | Deposit date: | 2021-02-15 | | Release date: | 2021-03-03 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase.
Nucleic Acids Res., 50, 2022
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7T2F
 | | Solution structure of the model HEEH mini protein homodimer HEEH_TK_rd5_0341 | | Descriptor: | HEEH mini protein HEEH_TK_rd5_0341 | | Authors: | Lemak, A, Houliston, S, Kim, T.-E, Martel, C, Rocklin, G.J, Arrowsmith, C.H. | | Deposit date: | 2021-12-04 | | Release date: | 2022-10-05 | | Last modified: | 2022-10-19 | | Method: | SOLUTION NMR | | Cite: | Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7UGC
 | | Structure of the N-terminal domain of ViaA | | Descriptor: | Protein ViaA | | Authors: | Lemak, A, Reichheld, S, Bhandari, V, Houliston, S, Arrowsmith, C.H, Sharpe, S, Houry, W.A. | | Deposit date: | 2022-03-24 | | Release date: | 2023-03-29 | | Method: | SOLUTION NMR | | Cite: | Structure of the N-terminal domain of ViaA
To Be Published
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6VFO
 | | Solution structure of the PHD of mouse UHRF1 (NP95) | | Descriptor: | E3 ubiquitin-protein ligase UHRF1, ZINC ION | | Authors: | Lemak, A, Houliston, S, Duan, S, Arrowsmith, C.H. | | Deposit date: | 2020-01-06 | | Release date: | 2020-06-17 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1.
Nucleic Acids Res., 48, 2020
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6VED
 | | Solution structure of the TTD and linker region of UHRF1 | | Descriptor: | E3 ubiquitin-protein ligase UHRF1 | | Authors: | Lemak, A, Houliston, S, Duan, S, Ong, M.S, Arrowsmith, C.H. | | Deposit date: | 2019-12-31 | | Release date: | 2020-06-17 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1.
Nucleic Acids Res., 48, 2020
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6VEE
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6VTI
 | | Solution NMR structure of the N-terminal domain of the Serine/threonine-protein phosphatase 1 regulatory subunit 10, PPP1R10 | | Descriptor: | Serine/threonine-protein phosphatase 1 regulatory subunit 10 | | Authors: | Lemak, A, Wei, Y, Duan, S, Houliston, S, Penn, L.Z, Arrowsmith, C.H. | | Deposit date: | 2020-02-12 | | Release date: | 2020-02-26 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase.
Nucleic Acids Res., 50, 2022
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5UYO
 | | Solution NMR structure of the de novo mini protein HEEH_rd4_0097 | | Descriptor: | HEEH_rd4_0097 | | Authors: | Lemak, A, Rocklin, G.J, Houliston, S, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H. | | Deposit date: | 2017-02-24 | | Release date: | 2017-07-26 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Global analysis of protein folding using massively parallel design, synthesis, and testing.
Science, 357, 2017
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2L7R
 | | Solution NMR structure of N-terminal Ubiquitin-like domain of FUBI, a ribosomal protein S30 precursor from Homo sapiens. NorthEast Structural Genomics consortium (NESG) target HR6166 | | Descriptor: | Ubiquitin-like protein FUBI | | Authors: | Lemak, A, Yee, A, Houliston, S, Semesi, A, Doherty, R, Dhe-Paganon, S, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC) | | Deposit date: | 2010-12-20 | | Release date: | 2011-01-05 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of N-terminal Ubiquitin-like domain of FUBI, a ribosomal protein S30
precursor from Homo sapiens. NorthEast Structural Genomics consortium (NESG) target HR6166
To be Published
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2LC3
 | | Solution NMR structure of a helical bundle domain from human E3 ligase HECTD1. Northeast structural genomics consortium (NESG) target HT6305A | | Descriptor: | E3 ubiquitin-protein ligase HECTD1 | | Authors: | Lemak, A, Yee, A, Houliston, S, Garcia, M, Arrowsmith, C, Dhe-Paganon, S, Montelione, G.T, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC) | | Deposit date: | 2011-04-15 | | Release date: | 2011-06-22 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of a helical bundle from the E3 ligase HECTD1
To be Published
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2LV9
 | | Solution NMR structure of the PHD domain of human MLL5, Northeast structural genomics consortium target HR6512A | | Descriptor: | Histone-lysine N-methyltransferase MLL5, ZINC ION | | Authors: | Lemak, A, Yee, A, Houliston, S, Garcia, M, Wu, H, Min, J, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC), Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS) | | Deposit date: | 2012-06-29 | | Release date: | 2012-09-05 | | Last modified: | 2012-11-28 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of the human MLL5 PHD domain (CASP Target)
To be Published
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2LLL
 | | Solution NMR structure of C-terminal globular domain of human Lamin-B2, Northeast Structural Genomics Consortium target HR8546A | | Descriptor: | Lamin-B2 | | Authors: | Lemak, A, Yee, A, Houliston, S, Garcia, M, Xu, C, Min, J, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC), Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS) | | Deposit date: | 2011-11-11 | | Release date: | 2011-12-07 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of c-terminal globular domain of human Lamin-B2
To be Published
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2LVA
 | | NMR solution structure of the N-terminal domain of human USP28, Northeast structural genomics consortium target HT8470A | | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 28 | | Authors: | Lemak, A, Yee, A, Houliston, S, Garcia, M, Dhe-Paganon, S, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC) | | Deposit date: | 2012-06-29 | | Release date: | 2012-07-18 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of the N-terminal domain of human USP28
To be Published
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2M2E
 | | Solution NMR structure of the SANT domain of human DNAJC2, Northeast structural genomics consortium target HR8254a | | Descriptor: | DnaJ homolog subfamily C member 2 | | Authors: | Lemak, A, Yee, A, Houliston, S, Garcia, M, Ong, M, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC) | | Deposit date: | 2012-12-18 | | Release date: | 2013-02-20 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of the SANT domain of human DnaJC2.
To be Published
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2KR1
 | | Solution NMR structure of zinc binding N-terminal domain of ubiquitin-protein ligase E3A from Homo Sapiens. Northeast Structural Genomics Consortium (NESG) target HR3662 | | Descriptor: | Ubiquitin protein ligase E3A, ZINC ION | | Authors: | Lemak, A, Yee, A, Fares, C, Semesi, A, Xiao, R, Montelione, G, Dhe-Paganon, S, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Structural Genomics Consortium (SGC) | | Deposit date: | 2009-11-27 | | Release date: | 2009-12-22 | | Last modified: | 2020-02-26 | | Method: | SOLUTION NMR | | Cite: | Zn-binding AZUL domain of human ubiquitin protein ligase Ube3A.
J.Biomol.Nmr, 51, 2011
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2K54
 | | Solution NMR structure of protein Atu0742 from Agrobacterium Tumefaciens. Northeast Structural Genomics Consortium (NESG0) target AtT8. Ontario Center for Structural Proteomics target ATC0727 . | | Descriptor: | Protein Atu0742 | | Authors: | Lemak, A, Yee, A, Gutmanas, A, Fares, C, Semesi, A, Arrowsmith, C, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-06-24 | | Release date: | 2008-08-19 | | Last modified: | 2020-02-19 | | Method: | SOLUTION NMR | | Cite: | Solution structure of protein ATC0727 from Agrobacterium Tumefaciens.
To be Published
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2K7I
 | | Solution NMR structure of protein ATU0232 from AGROBACTERIUM TUMEFACIENS. Northeast Structural Genomics Consortium (NESG) target AtT3. Ontario Center for Structural Proteomics target ATC0223. | | Descriptor: | UPF0339 protein Atu0232 | | Authors: | Lemak, A, Srisailam, S, Yee, A, Bansal, S, Semesi, A, Prestegard, J, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-08-12 | | Release date: | 2008-10-07 | | Last modified: | 2020-02-19 | | Method: | SOLUTION NMR | | Cite: | Solution structure of protein ATU0232 from Agrobacterium Tumefaciens.
To be Published
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2KJZ
 | | Solution NMR structure of protein ATC0852 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium (NESG) target AtT2. | | Descriptor: | ATC0852 | | Authors: | Lemak, A, Yee, A, Gutmanas, A, Fares, C, Garcia, M, Montelione, G, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-06-12 | | Release date: | 2009-07-07 | | Last modified: | 2020-02-26 | | Method: | SOLUTION NMR | | Cite: | Solution structure of protein ATC0852 from Agrobacterium tumefaciens
To be Published
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2KEO
 | | Solution NMR structure of human protein HS00059, cytochrome-b5-like domain of the HERC2 E3 ligase. Northeast structural genomics consortium (NESG) target ht98a | | Descriptor: | Probable E3 ubiquitin-protein ligase HERC2 | | Authors: | Lemak, A, Gutmanas, A, Fares, C, Quyang, H, Li, Y, Montelione, G, Arrowsmith, C, Dhe-Paganon, S, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-01-30 | | Release date: | 2009-02-24 | | Last modified: | 2012-01-18 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of human protein HS00059
To be Published
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2JQ5
 | | Solution structure of RPA3114, a SEC-C motif containing protein from Rhodopseudomonas palustris; Northeast Structural Genomics Consortium target RpT5 / Ontario Center for Structural Proteomics target RP3097 | | Descriptor: | SEC-C motif, ZINC ION | | Authors: | Lemak, A, Lukin, J, Yee, A, Gutmanas, A, Karra, M, Semesi, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP) | | Deposit date: | 2007-05-29 | | Release date: | 2007-06-26 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a Se-C motif containing protein from Rhodopseudomonas palustris
To be Published
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2JN4
 | | Solution NMR Structure of Protein RP4601 from Rhodopseudomonas palustris. Northeast Structural Genomics Consortium Target RpT2; Ontario Center for Structural Proteomics Target RP4601. | | Descriptor: | Hypothetical protein fixU, nifT | | Authors: | Lemak, A, Srisailam, S, Yee, A, Karra, M.D, Lukin, J.A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-12-22 | | Release date: | 2007-01-23 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a hypothetical protein RP4601 from Rhodopseudomonas palustris
To be Published
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2KCO
 | | Solution NMR structure of ribosomal protein sso0164 from Sulfolobus solfataricus. Northeast Structural Genomics Consortium (NESG) target SsT4. | | Descriptor: | 30S ribosomal protein S8e | | Authors: | Lemak, A, Gutmanas, A, Yee, A, Fares, C, Garcia, M, Montelione, G.T, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-12-23 | | Release date: | 2009-01-13 | | Last modified: | 2020-02-19 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of ribosomal protein sso0164 from Sulfolobus solfataricus
To be Published
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2KK4
 | | Solution NMR structure of protein AF2094 from Archaeoglobus fulgidus. Northeast Structural Genomics Consotium (NESG) target GT2 | | Descriptor: | Uncharacterized protein AF_2094 | | Authors: | Lemak, A, Yee, A, Wu, B, Karra, M, Ramelot, T, Fares, C, Semesi, A, Kennedy, M, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-06-15 | | Release date: | 2009-07-07 | | Last modified: | 2020-02-26 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of proterin AF2094 from Archaeoglobus fulgidus
To be Published
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2KZ6
 | | Solution structure of protein CV0426 from Chromobacterium violaceum, Northeast structural genomics consortium (NESG) target CVT2 | | Descriptor: | Uncharacterized protein | | Authors: | Lemak, A, Yee, A, Lee, H, Semesi, A, Prestegard, J, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-06-11 | | Release date: | 2010-06-30 | | Last modified: | 2020-02-05 | | Method: | SOLUTION NMR | | Cite: | Solution structure of protein CV0426 from Chromobacterium violaceum
To be Published
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2LEZ
 | | Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a | | Descriptor: | Secreted effector protein pipB2 | | Authors: | Lemak, A, Yee, A, Houliston, S, Garcia, M, Daniels, C, Savchenko, A, Arrowsmith, C, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2011-06-27 | | Release date: | 2011-07-27 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of N-terminal domain of Salmonella effector protein PipB2
To be Published
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