4W5A
Complex structure of ATRX ADD bound to H3K9me3S10ph peptide
Summary for 4W5A
Entry DOI | 10.2210/pdb4w5a/pdb |
Related | 3QL9 3QLA 3QLC 3QLN |
Descriptor | Transcriptional regulator ATRX, Peptide from Histone H3.3, ZINC ION, ... (4 entities in total) |
Functional Keywords | epigenetic regulation, complex, transcription, mitosis, hydrolase-structural protein complex, hydrolase/structural protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: P46100 P84243 |
Total number of polymer chains | 6 |
Total formula weight | 50033.86 |
Authors | |
Primary citation | Noh, K.M.,Maze, I.,Zhao, D.,Xiang, B.,Wenderski, W.,Lewis, P.W.,Shen, L.,Li, H.,Allis, C.D. ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons Proc.Natl.Acad.Sci.USA, 112:6820-6827, 2015 Cited by PubMed: 25538301DOI: 10.1073/pnas.1411258112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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