7EBK

Mouse Trim66 PHD-Bromo dual domain complexed with the H3(1-24)K9me3K18ac peptide

Summary for 7EBK

• Entry DOI: 10.2210/pdb7ebk/pdb
• Descriptor: Tripartite motif-containing protein 66, H3K9me3K18ac, ZINC ION, ... (4 entities in total)
• Functional Keywords: histone modification, phd finger, bromodomain, epigenetics, gene regulation
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 24302.91

Authors

Wang, Z.,Jiang, J. (deposition date: 2021-03-09, release date: 2022-03-09, Last modification date: 2023-11-29)

• Primary citation: Zuo, F.,Jiang, J.,Fu, H.,Yan, K.,Liefke, R.,Zhang, J.,Hong, Y.,Chang, Z.,Liu, N.,Wang, Z.,Xi, Q.; A TRIM66/DAX1/Dux axis suppresses the totipotent 2-cell-like state in murine embryonic stem cells.; Cell Stem Cell, 29:948-961.e6, 2022; PubMed: 35659877; DOI: 10.1016/j.stem.2022.05.004

Experimental method

X-RAY DIFFRACTION (1.74 Å)