Author results

1OSV
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STRUCTURAL BASIS FOR BILE ACID BINDING AND ACTIVATION OF THE NUCLEAR RECEPTOR FXR
Descriptor:Bile acid receptor, Nuclear receptor coactivator 2, 6-ETHYL-CHENODEOXYCHOLIC ACID
Authors:Mi, L.Z., Devarakonda, S., Harp, J.M., Han, Q., Pellicciari, R., Willson, T.M., Khorasanizadeh, S., Rastinejad, F.
Deposit date:2003-03-20
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
Mol.Cell, 11, 2003
1OT7
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STRUCTURAL BASIS FOR 3-DEOXY-CDCA BINDING AND ACTIVATION OF FXR
Descriptor:Bile Acid Receptor, dodecamer peptide fragment of RPGR-interacting protein 1, 6-ETHYL-CHENODEOXYCHOLIC ACID, ...
Authors:Mi, L.Z., Devarakonda, S., Harp, J.M., Han, Q., Pellicciari, R., Willson, T.M., Khorasanizadeh, S., Rastinejad, F.
Deposit date:2003-03-21
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
Mol.Cell, 11, 2003
4YCI
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NON-LATENT PRO-BONE MORPHOGENETIC PROTEIN 9
Descriptor:Bone Morphogenetic Protein 9 Growth Factor Domain, Bone Morphogenetic Protein 9 Prodomain, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mi, L.Z., Brown, C.T., Gao, Y., Tian, Y., Le, V., Walz, T., Springer, T.A.
Deposit date:2015-02-20
Release date:2015-03-04
Last modified:2015-08-26
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of bone morphogenetic protein 9 procomplex.
Proc.Natl.Acad.Sci.USA, 112, 2015
2AF9
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CRYSTAL STRUCTURE ANALYSIS OF GM2-ACTIVATOR PROTEIN COMPLEXED WITH PHOSPHATIDYLCHOLINE
Descriptor:Ganglioside GM2 activator, OLEIC ACID, MYRISTIC ACID, ...
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-25
Release date:2005-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AG2
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CRYSTAL STRUCTURE ANALYSIS OF GM2-ACTIVATOR PROTEIN COMPLEXED WITH PHOSPHATIDYLCHOLINE
Descriptor:Ganglioside GM2 activator, CHLORIDE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AG4
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CRYSTAL STRUCTURE ANALYSIS OF GM2-ACTIVATOR PROTEIN COMPLEXED WITH PHOSPHATIDYLCHOLINE
Descriptor:Ganglioside GM2 activator, (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE, OLEIC ACID, ...
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AG9
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CRYSTAL STRUCTURE OF THE Y137S MUTANT OF GM2-ACTIVATOR PROTEIN
Descriptor:Ganglioside GM2 activator, ISOPROPYL ALCOHOL, MYRISTIC ACID
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AGC
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CRYSTAL STRUCTURE OF MOUSE GM2- ACTIVATOR PROTEIN
Descriptor:Ganglioside GM2 activator, MYRISTIC ACID, LAURIC ACID
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
3VDJ
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CRYSTAL STRUCTURE OF CIRCUMSPOROZOITE PROTEIN ATSR DOMAIN, R32 NATIVE FORM
Descriptor:Circumsporozoite (CS) protein
Authors:Doud, M.B., Koksal, A.C., Mi, L.Z., Song, G., Lu, C., Springer, T.A.
Deposit date:2012-01-05
Release date:2012-05-09
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VDK
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CRYSTAL STRUCTURE OF CIRCUMSPOROZOITE PROTEIN ATSR DOMAIN, R32 PLATINUM-BOUND FORM
Descriptor:Circumsporozoite (CS) protein, PLATINUM (II) ION
Authors:Doud, M.B., Koksal, A.C., Mi, L.Z., Song, G., Lu, C., Springer, T.A.
Deposit date:2012-01-05
Release date:2012-05-09
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VDL
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CRYSTAL STRUCTURE OF CIRCUMSPOROZOITE PROTEIN ATSR DOMAIN, P43212 FORM
Descriptor:Circumsporozoite (CS) protein
Authors:Doud, M.B., Koksal, A.C., Mi, L.Z., Song, G., Lu, C., Springer, T.A.
Deposit date:2012-01-05
Release date:2012-05-09
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Unexpected fold in the circumsporozoite protein target of malaria vaccines.
Proc.Natl.Acad.Sci.USA, 109, 2012
5X8Y
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A MUTATION IDENTIFIED IN NEONATAL MICROCEPHALY DESTABILIZES ZIKA VIRUS NS1 ASSEMBLY IN VITRO
Descriptor:ZIKV NS1
Authors:Wang, D., Chen, C., Liu, S., Zhou, H., Yang, K., Zhao, Q., Ji, X., Chen, C., Xie, W., Wang, Z., Mi, L.Z., Yang, H.
Deposit date:2017-03-03
Release date:2017-05-17
Method:X-RAY DIFFRACTION (2.817 Å)
Cite:A Mutation Identified in Neonatal Microcephaly Destabilizes Zika Virus NS1 Assembly in Vitro
Sci Rep, 7, 2017
4YCG
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PRO-BONE MORPHOGENETIC PROTEIN 9
Descriptor:Bone Morphogenetic Protein 9 Growth Factor Domain, Bone Morphogenetic Protein 9 Prodomain, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mi, L.-Z., Brown, C.T., Gao, Y., Tian, Y., Le, V., Walz, T., Springer, T.A.
Deposit date:2015-02-20
Release date:2015-03-04
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of bone morphogenetic protein 9 procomplex.
Proc.Natl.Acad.Sci.USA, 112, 2015
2B2T
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TANDEM CHROMODOMAINS OF HUMAN CHD1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING TRIMETHYLLYSINE 4 AND PHOSPHOTHREONINE 3
Descriptor:Chromodomain-helicase-DNA-binding protein 1, Histone H3 tail
Authors:Flanagan IV, J.F., Mi, L.-Z., Chruszcz, M., Cymborowski, M., Clines, K.L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B2U
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TANDEM CHROMODOMAINS OF HUMAN CHD1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING TRIMETHYLLYSINE 4 AND DIMETHYLARGININE 2
Descriptor:Chromodomain-helicase-DNA-binding protein 1, Histone H3
Authors:Flanagan IV, J.F., Mi, L.-Z., Chruszcz, M., Cymborowski, M., Clines, K.L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B2V
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CRYSTAL STRUCTURE ANALYSIS OF HUMAN CHD1 CHROMODOMAINS 1 AND 2 BOUND TO HISTONE H3 RESI 1-15 MEK4
Descriptor:Chromodomain-helicase-DNA-binding protein 1, Histone H3
Authors:Flanagan IV, J.F., Mi, L.-Z., Chruszcz, M., Cymborowski, M., Clines, K.L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B2W
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TANDEM CHROMODOMAINS OF HUMAN CHD1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING TRIMETHYLLYSINE 4
Descriptor:Chromodomain-helicase-DNA-binding protein 1, Histone H3
Authors:Flanagan IV, J.F., Mi, L.-Z., Chruszcz, M., Cymborowski, M., Clines, K.L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B2Y
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TANDEM CHROMODOMAINS OF HUMAN CHD1
Descriptor:Chromodomain-helicase-DNA-binding protein 1
Authors:Flanagan IV, J.F., Mi, L.-Z., Chruszcz, M., Cymborowski, M., Clines, K.L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2OZ4
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STRUCTURAL PLASTICITY IN IGSF DOMAIN 4 OF ICAM-1 MEDIATES CELL SURFACE DIMERIZATION
Descriptor:Intercellular adhesion molecule 1, FAB FRAGMENT LIGHT CHAIN, FAB FRAGMENT, ...
Authors:Chen, X., Kim, T.D., Carman, C.V., Mi, L., Song, G., Springer, T.A.
Deposit date:2007-02-23
Release date:2007-10-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural plasticity in Ig superfamily domain 4 of ICAM-1 mediates cell surface dimerization.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3NJP
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THE EXTRACELLULAR AND TRANSMEMBRANE DOMAIN INTERFACES IN EPIDERMAL GROWTH FACTOR RECEPTOR SIGNALING
Descriptor:Epidermal growth factor receptor, Epidermal growth factor, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Lu, C., Mi, L.-Z., Grey, M.J., Zhu, J., Graef, E., Yokoyama, S., Springer, T.A.
Deposit date:2010-06-17
Release date:2010-10-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.304 Å)
Cite:Structural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor.
Mol.Cell.Biol., 30, 2010
4G1E
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CRYSTAL STRUCTURE OF INTEGRIN ALPHA V BETA 3 WITH COIL-COILED TAG.
Descriptor:Integrin alpha-V, Integrin beta-3, CALCIUM ION, ...
Authors:Dong, X., Mi, L., Zhu, J., Wang, W., Luo, B., Springer, T.A.
Deposit date:2012-07-10
Release date:2012-12-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:AlphaV Beta3 Integrin Crystal Structures and their Functional Implications
Biochemistry, 51, 2012
4G1M
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RE-REFINEMENT OF ALPHA V BETA 3 STRUCTURE
Descriptor:Integrin alpha-V, Integrin beta-3, CALCIUM ION, ...
Authors:Springer, T.A., Mi, L., Zhu, J.
Deposit date:2012-07-10
Release date:2012-12-05
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Alpha V Beta 3 Integrin Crystal Structures and their Functional Implications
Biochemistry, 51, 2012
3V4P
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CRYSTAL STRUCTURE OF A4B7 HEADPIECE COMPLEXED WITH FAB ACT-1
Descriptor:Integrin alpha-4, Integrin beta-7, MONOCLONAL ANTIBODY Act-1 HEAVY CHAIN, ...
Authors:Yu, Y., Zhu, J., Springer, T.A.
Deposit date:2011-12-15
Release date:2012-01-11
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion
J.Cell Biol., 196, 2012
3V4V
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CRYSTAL STRUCTURE OF A4B7 HEADPIECE COMPLEXED WITH FAB ACT-1 AND RO0505376
Descriptor:Integrin alpha-4, Integrin beta-7, MONOCLONAL ANTIBODY Act-1 HEAVY CHAIN, ...
Authors:Yu, Y., Zhu, J., Springer, T.A.
Deposit date:2011-12-15
Release date:2012-01-11
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural specializations of a4b7, an Integrin that Mediates Rolling Adhesion
J.Cell Biol., 196, 2012
5I05
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CRYSTAL STRUCTURE OF HUMAN BMP9 AT 1.87 A RESOLUTION
Descriptor:Growth/differentiation factor 2, GLYCEROL
Authors:Saito, T., Bokhove, M., Jovine, L.
Deposit date:2016-02-03
Release date:2017-06-07
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.
Cell Rep, 19, 2017