2AG4

Crystal Structure Analysis of GM2-activator protein complexed with phosphatidylcholine

Summary for 2AG4

• Entry DOI: 10.2210/pdb2ag4/pdb
• Related: 1G13 1PU5 1PUB 1TJJ
• Descriptor: Ganglioside GM2 activator, (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE, OLEIC ACID, ... (5 entities in total)
• Functional Keywords: complex of single chain lipid and fatty acids, lipid binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Lysosome: P17900
• Total number of polymer chains: 2
• Total formula weight: 37990.56

Authors

Wright, C.S.,Mi, L.Z.,Lee, S.,Rastinejad, F. (deposition date: 2005-07-26, release date: 2005-10-25, Last modification date: 2023-08-23)

• Primary citation: Wright, C.S.,Mi, L.Z.,Lee, S.,Rastinejad, F.; Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.; Biochemistry, 44:13510-13521, 2005; PubMed: 16216074; DOI: 10.1021/bi050668w

Experimental method

X-RAY DIFFRACTION (1.8 Å)