2B2U

Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and dimethylarginine 2

Summary for 2B2U

Related1kna 1kne 1q3l 1pdq 2b2t 2b2v 2b2w 2b2y
DescriptorChromodomain-helicase-DNA-binding protein 1, Histone H3 (3 entities in total)
Functional Keywordschd, chromodomain, three stranded antiparallel beta sheet, alpha helix linker, histone h3, asymmetric dimethylarginine, trimethyllysine, peptide binding protein
Biological sourceHomo sapiens (human)
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Cellular locationNucleus  O14646 O14646 P68431
Total number of polymer chains4
Total molecular weight59785.91
Authors
Flanagan IV, J.F.,Mi, L.-Z.,Chruszcz, M.,Cymborowski, M.,Clines, K.L.,Kim, Y.,Minor, W.,Rastinejad, F.,Khorasanizadeh, S. (deposition date: 2005-09-19, release date: 2005-12-27, Last modification date: 2017-10-11)
Primary citation
Flanagan, J.F.,Mi, L.Z.,Chruszcz, M.,Cymborowski, M.,Clines, K.L.,Kim, Y.,Minor, W.,Rastinejad, F.,Khorasanizadeh, S.
Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438:1181-1185, 2005
PubMed: 16372014 (PDB entries with the same primary citation)
DOI: 10.1038/nature04290
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.95 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.276406.7%14.5%0.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2b2u
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Molmil generated image of 2b2u
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Molmil generated image of 2b2u
rotated about y axis by 90°