2AG2
Crystal Structure Analysis of GM2-activator protein complexed with Phosphatidylcholine
Summary for 2AG2
Entry DOI | 10.2210/pdb2ag2/pdb |
Related | 1G13 1PU5 1PUB 1TJJ |
Descriptor | Ganglioside GM2 activator, CHLORIDE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (10 entities in total) |
Functional Keywords | phospholipid-protein complex, lipid acyl chain stacking, packaging, lipid binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Lysosome: P17900 |
Total number of polymer chains | 3 |
Total formula weight | 58503.79 |
Authors | Wright, C.S.,Mi, L.Z.,Lee, S.,Rastinejad, F. (deposition date: 2005-07-26, release date: 2005-10-25, Last modification date: 2023-08-23) |
Primary citation | Wright, C.S.,Mi, L.Z.,Lee, S.,Rastinejad, F. Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity. Biochemistry, 44:13510-13521, 2005 Cited by PubMed: 16216074DOI: 10.1021/bi050668w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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