2AG2
Crystal Structure Analysis of GM2-activator protein complexed with Phosphatidylcholine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Ganglioside GM2 activator | polymer | 164 | 17827.6 | 3 | UniProt (P17900) Pfam (PF02221) | Homo sapiens (human) | GM2-AP |
| 2 | D, J, S (A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 3 | E, T (A, C) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 4 | F, G, L, V (A, B, C) | (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE | non-polymer | 524.7 | 4 | Chemie (LP3) | |||
| 5 | AA, BA, CA, H, I... (C, A, B) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 10 | Chemie (IPA) | |||
| 6 | K, U (B, C) | 2-(((R)-2,3-DIHYDROXYPROPYL)PHOSPHORYLOXY)-N,N,N-TRIMETHYLETHANAMINIUM | non-polymer | 258.2 | 2 | Chemie (CH5) | |||
| 7 | M, W (B, C) | OLEIC ACID | non-polymer | 282.5 | 2 | Chemie (OLA) | |||
| 8 | N, X (B, C) | MYRISTIC ACID | non-polymer | 228.4 | 2 | Chemie (MYR) | |||
| 9 | O (B) | LAURIC ACID | non-polymer | 200.3 | 1 | Chemie (DAO) | |||
| 10 | DA, EA, FA (A, B, C) | water | water | 18.0 | 594 | Chemie (HOH) |
Sequence modifications
A, B, C: 3 - 164 (UniProt: P17900)
| PDB | External Database | Details |
|---|---|---|
| His 1 | - | cloning artifact |
| Met 2 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 53482.7 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 5021.1 | |
| All* | Total formula weight | 58503.8 |
