2AG9
Crystal Structure of the Y137S mutant of GM2-Activator Protein
Summary for 2AG9
Entry DOI | 10.2210/pdb2ag9/pdb |
Related | 1G13 1PU5 1PUB 1TJJ 2AG2 2AG4 |
Descriptor | Ganglioside GM2 activator, ISOPROPYL ALCOHOL, MYRISTIC ACID, ... (4 entities in total) |
Functional Keywords | conformational changes in mobile loop (w131 loop), lipid binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Lysosome: P17900 |
Total number of polymer chains | 2 |
Total formula weight | 36572.62 |
Authors | Wright, C.S.,Mi, L.Z.,Lee, S.,Rastinejad, F. (deposition date: 2005-07-26, release date: 2005-10-25, Last modification date: 2023-08-23) |
Primary citation | Wright, C.S.,Mi, L.Z.,Lee, S.,Rastinejad, F. Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity. Biochemistry, 44:13510-13521, 2005 Cited by PubMed: 16216074DOI: 10.1021/bi050668w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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