2AG9
Crystal Structure of the Y137S mutant of GM2-Activator Protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ganglioside GM2 activator | polymer | 164 | 17751.5 | 2 | UniProt (P17900) Pfam (PF02221) | Homo sapiens (human) | GM2-AP |
| 2 | C, D, E, F, G... (A, B) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 14 | Chemie (IPA) | |||
| 3 | M (B) | MYRISTIC ACID | non-polymer | 228.4 | 1 | Chemie (MYR) | |||
| 4 | R, S (A, B) | water | water | 18.0 | 279 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 164 (UniProt: P17900)
| PDB | External Database | Details |
|---|---|---|
| His 1 | - | cloning artifact |
| Met 2 | - | cloning artifact |
| Ser 139 | Tyr 168 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35502.9 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1069.7 | |
| All* | Total formula weight | 36572.6 |
