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2AG9

Crystal Structure of the Y137S mutant of GM2-Activator Protein

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Ganglioside GM2 activatorpolymer16417751.52UniProt (P17900)
Pfam (PF02221)
Homo sapiens (human)GM2-AP
2C, D, E, F, G...
(A, B)
ISOPROPYL ALCOHOLnon-polymer60.114Chemie (IPA)
3M
(B)
MYRISTIC ACIDnon-polymer228.41Chemie (MYR)
4R, S
(A, B)
waterwater18.0279Chemie (HOH)
Sequence modifications
A, B: 3 - 164 (UniProt: P17900)
PDBExternal DatabaseDetails
His 1-cloning artifact
Met 2-cloning artifact
Ser 139Tyr 168engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight35502.9
Non-Polymers*Number of molecules15
Total formula weight1069.7
All*Total formula weight36572.6
*Water molecules are not included.

238582

PDB entries from 2025-07-09

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