2AF9

Crystal Structure analysis of GM2-Activator protein complexed with phosphatidylcholine

Summary for 2AF9

• Entry DOI: 10.2210/pdb2af9/pdb
• Related: 1G13 1PU5 1PUB 1TJJ
• Descriptor: Ganglioside GM2 activator, OLEIC ACID, MYRISTIC ACID, ... (6 entities in total)
• Functional Keywords: lipid-protein complex, lipid acyl chain stacking, lipid binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Lysosome: P17900
• Total number of polymer chains: 1
• Total formula weight: 18859.21

Authors

Wright, C.S.,Mi, L.Z.,Lee, S.,Rastinejad, F. (deposition date: 2005-07-25, release date: 2005-10-25, Last modification date: 2023-08-23)

• Primary citation: Wright, C.S.,Mi, L.Z.,Lee, S.,Rastinejad, F.; Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.; Biochemistry, 44:13510-13521, 2005; PubMed: 16216074; DOI: 10.1021/bi050668w

Experimental method

X-RAY DIFFRACTION (2 Å)