Author results

6MJZ
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CRYO-EM STRUCTURE OF HUMAN PARAINFLUENZA VIRUS TYPE 3 (HPIV3) IN COMPLEX WITH ANTIBODY PIA174
Descriptor:Fusion glycoprotein F0, PIA174 Fab Heavy chain, PIA174 Fab Light chain
Authors:Acharya, P., Stewart-Jones, G., Carragher, B., Potter, C.S., Kwong, P.D.
Deposit date:2018-09-24
Release date:2018-11-14
Last modified:2018-12-12
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4ZWJ
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CRYSTAL STRUCTURE OF RHODOPSIN BOUND TO ARRESTIN BY FEMTOSECOND X-RAY LASER
Descriptor:Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin
Authors:Kang, Y., Zhou, X.E., Gao, X., He, Y., Liu, W., Ishchenko, A., Barty, A., White, T.A., Yefanov, O., Han, G.W., Xu, Q., de Waal, P.W., Ke, J., Tan, M.H.E., Zhang, C., Moeller, A., West, G.M., Pascal, B., Eps, N.V., Caro, L.N., Vishnivetskiy, S.A., Lee, R.J., Suino-Powell, K.M., Gu, X., Pal, K., Ma, J., Zhi, X., Boutet, S., Williams, G.J., Messerschmidt, M., Gati, C., Zatsepin, N.A., Wang, D., James, D., Basu, S., Roy-Chowdhury, S., Conrad, C., Coe, J., Liu, H., Lisova, S., Kupitz, C., Grotjohann, I., Fromme, R., Jiang, Y., Tan, M., Yang, H., Li, J., Wang, M., Zheng, Z., Li, D., Howe, N., Zhao, Y., Standfuss, J., Diederichs, K., Dong, Y., Potter, C.S., Carragher, B., Caffrey, M., Jiang, H., Chapman, H.N., Spence, J.C.H., Fromme, P., Weierstall, U., Ernst, O.P., Katritch, V., Gurevich, V.V., Griffin, P.R., Hubbell, W.L., Stevens, R.C., Cherezov, V., Melcher, K., Xu, H.E., GPCR Network (GPCR)
Deposit date:2015-05-19
Release date:2015-07-29
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (3.302 Å)
Cite:Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Nature, 523, 2015
6B3Q
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CRYO-EM STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH INSULIN
Descriptor:Insulin-degrading enzyme, Insulin
Authors:Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
Deposit date:2017-09-22
Release date:2017-11-22
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B70
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CRYO-EM STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH FAB H11-E HEAVY CHAIN, FAB H11-E LIGHT CHAIN AND INSULIN
Descriptor:Insulin-degrading enzyme, FAB H11-E heavy chain, FAB H11-E light chain, ...
Authors:Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
Deposit date:2017-10-03
Release date:2017-12-27
Last modified:2018-04-11
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B7Y
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CRYO-EM STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME
Descriptor:Insulin-degrading enzyme
Authors:Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
Deposit date:2017-10-05
Release date:2017-11-08
Last modified:2018-04-11
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B7Z
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CRYO-EM STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH FAB H11 HEAVY CHAIN AND FAB H11 LIGHT CHAIN
Descriptor:Insulin-degrading enzyme, FAB H11 heavy chain, FAB H11 light chain
Authors:Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
Deposit date:2017-10-05
Release date:2018-01-10
Last modified:2018-04-11
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF6
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CRYO-EM STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME
Descriptor:Insulin-degrading enzyme
Authors:Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
Deposit date:2017-10-26
Release date:2018-02-07
Last modified:2018-04-18
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF7
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CRYO-EM STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH FAB H11-E HEAVY CHAIN, FAB H11-E LIGHT CHAIN
Descriptor:Insulin-degrading enzyme, Fab H11-E heavy chain, Fab H11-E light chain
Authors:Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
Deposit date:2017-10-26
Release date:2018-02-07
Last modified:2018-04-11
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF8
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CRYO-EM STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH INSULIN
Descriptor:Insulin-degrading enzyme
Authors:Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
Deposit date:2017-10-26
Release date:2018-04-04
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF9
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CRYO-EM STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH FAB H11-E HEAVY CHAIN, FAB H11-E LIGHT CHAIN
Descriptor:Insulin-degrading enzyme, Fab H11-E heavy chain, Fab H11-E light chain
Authors:Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
Deposit date:2017-10-26
Release date:2018-02-07
Last modified:2018-04-11
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BFC
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CRYO-EM STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH INSULIN
Descriptor:Insulin-degrading enzyme, Insulin
Authors:Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
Deposit date:2017-10-26
Release date:2017-12-27
Last modified:2018-04-11
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6CDE
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CRYO-EM STRUCTURE AT 3.8 A RESOLUTION OF VACCINE-ELICITED ANTIBODY VFP20.01 IN COMPLEX WITH HIV-1 ENV BG505 DS-SOSIP, AND ANTIBODIES VRC03 AND PGT122
Descriptor:vFP20.01 Heavy Chain, vFP20.01 Light chain, PGT122 Heavy chain, ...
Authors:Acharya, P., Xu, K., Liu, K., Carragher, B., Potter, C.S., Kwong, P.D.
Deposit date:2018-02-08
Release date:2018-05-16
Last modified:2018-06-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
6CDI
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CRYO-EM STRUCTURE AT 3.6 A RESOLUTION OF VACCINE-ELICITED ANTIBODY VFP16.02 IN COMPLEX WITH HIV-1 ENV BG505 DS-SOSIP, AND ANTIBODIES VRC03 AND PGT122
Descriptor:Glycoprotein gp41, Glycoprotein 120, PGT122 Light Chain, ...
Authors:Acharya, P., Xu, K., Liu, K., Carragher, B., Potter, C.S., Kwong, P.D.
Deposit date:2018-02-08
Release date:2018-05-16
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Nat. Med., 24, 2018
6CUE
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CRYO-EM STRUCTURE AT 4.0 A RESOLUTION OF VACCINE-ELICITED ANTIBODY VFP7.04 IN COMPLEX WITH HIV-1 ENV BG505 DS-SOSIP, AND ANTIBODIES VRC03 AND PGT122
Descriptor:Envelope glycoprotein gp120, Envelope glycoprotein gp41, vFP7.04 Heavy chain, ...
Authors:Acharya, P., Carragher, B., Potter, C.S., Kwong, P.D.
Deposit date:2018-03-26
Release date:2018-07-11
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.
PLoS Pathog., 14, 2018
6CUF
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CRYO-EM STRUCTURE AT 4.2 A RESOLUTION OF VACCINE-ELICITED ANTIBODY VFP1.01 IN COMPLEX WITH HIV-1 ENV BG505 DS-SOSIP, AND ANTIBODIES VRC03 AND PGT122
Descriptor:vFP1.01 heavy chain, vFP1.01 Light chain, PGT122 Heavy chain, ...
Authors:Acharya, P., Carragher, B., Potter, C.S., Kwong, P.D.
Deposit date:2018-03-26
Release date:2018-07-25
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.
PLoS Pathog., 14, 2018
2YMN
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ORGANIZATION OF THE INFLUENZA VIRUS REPLICATION MACHINERY
Descriptor:NUCLEOPROTEIN
Authors:Moeller, A., Kirchdoerfer, R.N., Potter, C.S., Carragher, B., Wilson, I.A.
Deposit date:2012-10-09
Release date:2012-12-05
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Organization of the Influenza Virus Replication Machinery.
Science, 338, 2012
4C3G
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CRYO-EM STRUCTURE OF ACTIVATED AND OLIGOMERIC RESTRICTION ENDONUCLEASE SGRAI
Descriptor:SGRAIR RESTRICTION ENZYME, 5'-D(*GP*AP*TP*GP*CP*GP*TP*GP*GP*GP*TP*CP*TP*TP *CP*AP*CP*AP)-3', 5'-D(*CP*CP*GP*GP*TP*GP*TP*GP*AP*AP*GP*AP*CP*CP *CP*AP*CP*GP*CP*AP*TP*CP)-3'
Authors:Lyumkis, D., Talley, H., Stewart, A., Shah, S., Park, C.K., Tama, F., Potter, C.S., Carragher, B., Horton, N.C.
Deposit date:2013-08-23
Release date:2013-09-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.6 Å)
Cite:Allosteric Regulation of DNA Cleavage and Sequence-Specificity Through Run-on Oligomerization.
Structure, 21, 2013
5U1F
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INITIAL CONTACT OF HIV-1 ENV WITH CD4: CRYO-EM STRUCTURE OF BG505 DS-SOSIP TRIMER IN COMPLEX WITH CD4 AND ANTIBODY PGT145
Descriptor:BG505 DS-SOSIP gp120, BG505 SOSIP gp41, PGT145 heavy chain, ...
Authors:Acharya, P., Kwong, P.D., Potter, C.S., Carragher, B.
Deposit date:2016-11-28
Release date:2017-02-22
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer.
Nat. Struct. Mol. Biol., 24, 2017
6BDF
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2.8 A RESOLUTION RECONSTRUCTION OF THE THERMOPLASMA ACIDOPHILUM 20S PROTEASOME USING CRYO-ELECTRON MICROSCOPY
Descriptor:Proteasome subunit alpha, Proteasome subunit beta
Authors:Campbell, M.G., Veesler, D., Cheng, A., Potter, C.S., Carragher, B.
Deposit date:2017-10-23
Release date:2017-12-27
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:2.8 angstrom resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy.
Elife, 4, 2015
6CE7
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INSULIN RECEPTOR ECTODOMAIN IN COMPLEX WITH ONE INSULIN MOLECULE
Descriptor:Insulin receptor, Insulin A chain, Insulin B chain, ...
Authors:Scapin, G., Dandey, V.P., Zhang, Z., Strickland, C., Potter, C.S., Carragher, B.
Deposit date:2018-02-11
Release date:2018-03-14
Last modified:2018-04-18
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.
Nature, 556, 2018
6CE9
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INSULIN RECEPTOR ECTODOMAIN IN COMPLEX WITH TWO INSULIN MOLECULES
Descriptor:Insulin receptor, Insulin A chain, Insulin B chain, ...
Authors:Scapin, G., Dandey, V.P., Zhang, Z., Strickland, C., Potter, C.S., Carragher, B.
Deposit date:2018-02-11
Release date:2018-03-14
Last modified:2018-04-18
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.
Nature, 556, 2018
6CEB
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INSULIN RECEPTOR ECTODOMAIN IN COMPLEX WITH TWO INSULIN MOLECULES - C1 SYMMETRY
Descriptor:Insulin receptor, Insulin A chain, Insulin B chain, ...
Authors:Scapin, G., Dandey, V.P., Zhang, Z., Strickland, C., Potter, C.S., Carragher, B.
Deposit date:2018-02-11
Release date:2018-03-14
Last modified:2018-04-18
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.
Nature, 556, 2018
6N4V
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CRYOEM STRUCTURE OF LEVIVIRIDAE PP7 WT COAT PROTEIN DIMER CAPSID (PP7PP7-WT)
Descriptor:Coat protein
Authors:Liangjun, Z., Kopylov, M., Potter, C.S., Carragher, B., Finn, M.G.
Deposit date:2018-11-20
Release date:2019-04-03
Last modified:2019-05-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Engineering the PP7 Virus Capsid as a Peptide Display Platform.
Acs Nano, 13, 2019
6E6B
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CRYSTAL STRUCTURE OF THE PROTOCADHERIN GAMMAB4 EXTRACELLULAR DOMAIN
Descriptor:Protocadherin gamma B4, CALCIUM ION, ALPHA-D-MANNOSE, ...
Authors:Goodman, K.M., Mannepalli, S., Bahna, F., Honig, B., Shapiro, L.
Deposit date:2018-07-24
Release date:2019-04-10
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (4.52 Å)
Cite:Visualization of clustered protocadherin neuronal self-recognition complexes.
Nature, 569, 2019
6CV7
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MOUSE PROTOCADHERIN-15 EXTRACELLULAR CADHERIN DOMAINS 1 THROUGH 3
Descriptor:Protocadherin-15, CALCIUM ION, 1,2-ETHANEDIOL, ...
Authors:Dionne, G., Shapiro, L.
Deposit date:2018-03-27
Release date:2018-08-01
Method:X-RAY DIFFRACTION (1.692 Å)
Cite:Cis-dimeric architecture of Pcdh15 critical for mechanotransduction
Neuron, 2018
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