1A1X
 
 | | CRYSTAL STRUCTURE OF MTCP-1 INVOLVED IN T CELL MALIGNANCIES | | Descriptor: | HMTCP-1 | | Authors: | Fu, Z.Q, Dubois, G.C, Song, S.P, Kulikovskaya, I, Virgilio, L, Rothstein, J, Croce, C.M, Weber, I.T, Harrison, R.W. | | Deposit date: | 1997-12-18 | | Release date: | 1998-05-27 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of MTCP-1: implications for role of TCL-1 and MTCP-1 in T cell malignancies.
Proc.Natl.Acad.Sci.USA, 95, 1998
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1FUG
 | | S-ADENOSYLMETHIONINE SYNTHETASE | | Descriptor: | S-ADENOSYLMETHIONINE SYNTHETASE | | Authors: | Fu, Z, Markham, G.D, Takusagawa, F. | | Deposit date: | 1996-02-25 | | Release date: | 1996-08-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Flexible loop in the structure of S-adenosylmethionine synthetase crystallized in the tetragonal modification.
J.Biomol.Struct.Dyn., 13, 1996
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1KVK
 | | The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, mevalonate kinase | | Authors: | Fu, Z, Wang, M, Potter, D, Mizioko, H.M, Kim, J.J. | | Deposit date: | 2002-01-26 | | Release date: | 2002-03-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The Structure of a Binary complex
between a Mammalian Mevalonate Kinase and ATP: Insights into the
Reaction Mechanism and Human Inherited Disease
J.Biol.Chem., 277, 2002
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1ZTD
 | | Hypothetical Protein Pfu-631545-001 From Pyrococcus furiosus | | Descriptor: | Hypothetical Protein Pfu-631545-001 | | Authors: | Fu, Z.-Q, Horanyi, P, Florence, Q, Liu, Z.-J, Chen, L, Lee, D, Habel, J, Xu, H, Nguyen, D, Chang, S.-H, Zhou, W, Zhang, H, Jenney Jr, F.E, Sha, B, Adams, M.W.W, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | | Deposit date: | 2005-05-26 | | Release date: | 2005-06-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Hypothetical Protein Pfu-631545-001 From Pyrococcus furiosus
To be Published
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2CW6
 | | Crystal Structure of Human HMG-CoA Lyase: Insights into Catalysis and the Molecular Basis for Hydroxymethylglutaric Aciduria | | Descriptor: | 3-HYDROXYPENTANEDIOIC ACID, Hydroxymethylglutaryl-CoA lyase, mitochondrial, ... | | Authors: | Fu, Z, Runquist, J.A, Hunt, J.F, Miziorko, H.M, Kim, J.-J.P. | | Deposit date: | 2005-06-17 | | Release date: | 2005-12-06 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of human 3-hydroxy-3-methylglutaryl-CoA Lyase: insights into catalysis and the molecular basis for hydroxymethylglutaric aciduria
J.Biol.Chem., 281, 2006
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2FZF
 | | Hypothetical Protein Pfu-1136390-001 From Pyrococcus furiosus | | Descriptor: | hypothetical protein | | Authors: | Fu, Z.-Q, Liu, Z.-J, Lee, D, Kelley, L, Chen, L, Tempel, W, Shah, N, Horanyi, P, Lee, H.S, Habel, J, Dillard, B.D, Nguyen, D, Chang, S.-H, Zhang, H, Chang, J, Sugar, F.J, Poole, F.L, Jenney Jr, F.E, Adams, M.W.W, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | | Deposit date: | 2006-02-09 | | Release date: | 2006-02-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Hypothetical Protein Pfu-1136390-001 From Pyrococcus furiosus
To be published
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1XVA
 | | METHYLTRANSFERASE | | Descriptor: | ACETATE ION, GLYCINE N-METHYLTRANSFERASE, S-ADENOSYLMETHIONINE | | Authors: | Fu, Z, Hu, Y, Konishi, K, Takata, Y, Ogawa, H, Gomi, T, Fujioka, M, Takusagawa, F. | | Deposit date: | 1996-07-20 | | Release date: | 1997-01-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of glycine N-methyltransferase from rat liver.
Biochemistry, 35, 1996
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2G7P
 | | Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors | | Descriptor: | Botulinum neurotoxin type A, ZINC ION | | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | | Deposit date: | 2006-02-28 | | Release date: | 2006-08-15 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
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6ORL
 | | RF1 pre-accommodated 70S complex at 24 ms | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | | Deposit date: | 2019-04-30 | | Release date: | 2019-06-19 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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6OT3
 | | RF2 accommodated state bound Release complex 70S at 24 ms | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | | Deposit date: | 2019-05-02 | | Release date: | 2019-06-19 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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6OST
 | | RF2 pre-accommodated state bound Release complex 70S at 24ms | | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | | Deposit date: | 2019-05-02 | | Release date: | 2019-06-19 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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2G7N
 | | Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to small Molecule Inhibitors | | Descriptor: | Botulinum neurotoxin type A, SILVER ION, ZINC ION | | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | | Deposit date: | 2006-02-28 | | Release date: | 2007-03-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of the Light Chain of Botulinum Neurotoxin Serotype A bound to Small Molecule Inhibitors
To be Published
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2G7K
 | | Structure of the Light Chain of Botulinum Neurotoxin, Serotype A Bound to small Molecule Inhibitors | | Descriptor: | Botulinum neurotoxin type A | | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Crawford, A, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | | Deposit date: | 2006-02-28 | | Release date: | 2006-08-15 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
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2G7Q
 | | Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors | | Descriptor: | Botulinum neurotoxin type A, N-HYDROXY-L-ARGININAMIDE, ZINC ION | | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | | Deposit date: | 2006-02-28 | | Release date: | 2006-08-15 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
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6ORE
 | | Release complex 70S | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Fu, Z. | | Deposit date: | 2019-04-30 | | Release date: | 2019-06-19 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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6OSK
 | | RF1 accommodated 70S complex at 60 ms | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | | Deposit date: | 2019-05-01 | | Release date: | 2019-06-26 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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6OSQ
 | | RF1 accommodated state bound Release complex 70S at long incubation time point | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | | Deposit date: | 2019-05-02 | | Release date: | 2019-06-26 | | Last modified: | 2020-01-08 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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6OUO
 | | RF2 accommodated state bound 70S complex at long incubation time | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | | Deposit date: | 2019-05-05 | | Release date: | 2019-06-19 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
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6DV2
 | | Crystal Structure of Human Mitochondrial Trifunctional Protein | | Descriptor: | Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta | | Authors: | Fu, Z, Xia, C, Battaile, K.P, Kim, J.P. | | Deposit date: | 2018-06-22 | | Release date: | 2018-09-26 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Crystal structure of human mitochondrial trifunctional protein, a fatty acid beta-oxidation metabolon.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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3RMY
 | | Crystal structure of HCR/D W1238A mutant | | Descriptor: | Botulinum neurotoxin type D, GLYCEROL | | Authors: | Fu, Z, Karalewitz, A, Kroken, A, Kim, J.-J.P, Barbieri, J.T. | | Deposit date: | 2011-04-21 | | Release date: | 2011-06-01 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Novel Ganglioside-mediated Entry of Botulinum Neurotoxin Serotype D into Neurons.
J.Biol.Chem., 286, 2011
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3RSJ
 | | Structure of HCRF in complex with Ganglioside GD1a | | Descriptor: | BoNT/F, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose, ... | | Authors: | Fu, Z, Benson, M.A, Barbieri, J.T, Kim, J.-J.P, Baldwin, M.R. | | Deposit date: | 2011-05-02 | | Release date: | 2011-08-17 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Unique ganglioside recognition strategies for clostridial neurotoxins.
J.Biol.Chem., 286, 2011
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8GXR
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4FVV
 | | Crystal structure of HCR/D-Sa-GBL1/C | | Descriptor: | GLYCEROL, N-acetyl-alpha-neuraminic acid, Neurotoxin, ... | | Authors: | Fu, Z, Karalewitz, A, Baldwin, M.R, Kim, J.-J.P, Barbieri, J.T. | | Deposit date: | 2012-06-29 | | Release date: | 2012-10-24 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry.
J.Biol.Chem., 287, 2012
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4IQP
 | | Crystal Structure of HCRA-W1266A | | Descriptor: | Botulinum neurotoxin type A, GLYCEROL | | Authors: | Fu, Z, Kroken, A.R, Barbieri, J.T, Kim, J.-J.P. | | Deposit date: | 2013-01-12 | | Release date: | 2013-05-29 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Enhancing the Protective Immune Response against Botulism.
Infect.Immun., 81, 2013
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3FUQ
 | | Glycosylated SV2 and Gangliosides as Dual Receptors for Botulinum Neurotoxin Serotype F | | Descriptor: | BoNT/F (Neurotoxin type F) | | Authors: | Fu, Z, Chen, C, Barbieri, J.T, Kim, J.-J.P, Baldwin, M.R. | | Deposit date: | 2009-01-14 | | Release date: | 2009-06-16 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F
Biochemistry, 48, 2009
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