2G7Q
Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors
Summary for 2G7Q
Entry DOI | 10.2210/pdb2g7q/pdb |
Related | 2G7K 2G7N 2G7P |
Descriptor | Botulinum neurotoxin type A, ZINC ION, N-HYDROXY-L-ARGININAMIDE, ... (4 entities in total) |
Functional Keywords | botulinum neurotoxin, zinc protease, snap25, hydrolase |
Biological source | Clostridium botulinum |
Cellular location | Botulinum neurotoxin A light chain: Secreted. Botulinum neurotoxin A heavy chain: Secreted: Q45894 |
Total number of polymer chains | 2 |
Total formula weight | 97737.57 |
Authors | Fu, Z.,Baldwin, M.R.,Boldt, G.E.,Janda, K.D.,Barbieri, J.T.,Kim, J.-J.P. (deposition date: 2006-02-28, release date: 2006-08-15, Last modification date: 2023-08-30) |
Primary citation | Fu, Z.,Chen, S.,Baldwin, M.R.,Boldt, G.E.,Crawford, A.,Janda, K.D.,Barbieri, J.T.,Kim, J.J. Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate. Biochemistry, 45:8903-8911, 2006 Cited by PubMed: 16846233DOI: 10.1021/bi060786z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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