2G7Q
Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 451 |
| Chain | Residue |
| B | HIS222 |
| B | HIS226 |
| B | GLU261 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 452 |
| Chain | Residue |
| A | HIS222 |
| A | HIS226 |
| A | GLU261 |
| A | AHL500 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE AHL A 500 |
| Chain | Residue |
| A | HIS222 |
| A | GLU223 |
| A | HIS226 |
| A | GLU261 |
| A | ASP369 |
| A | ZN452 |
| A | PHE162 |
| A | PHE193 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15107500","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16846233","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2G7P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2G7Q","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"PubMed","id":"16846233","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
