2G7Q
Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Botulinum neurotoxin type A | polymer | 425 | 48708.8 | 2 | UniProt (Q45894) Pfam (PF01742) | Clostridium botulinum | |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | N-HYDROXY-L-ARGININAMIDE | non-polymer | 189.2 | 1 | Chemie (AHL) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 425 (UniProt: Q45894)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ala 362 | Arg 362 | engineered mutation |
| Phe 365 | Tyr 365 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97417.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 320.0 | |
| All* | Total formula weight | 97737.6 |
