3LYR
| Human Early B-cell Factor 1 (EBF1) DNA-binding domain | Descriptor: | AMMONIUM ION, SULFATE ION, Transcription factor COE1, ... | Authors: | Siponen, M.I, Wisniewska, M, Arrowsmith, C.H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kraulis, P, Kotenyova, T, Markova, N, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schuler, H, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Berglund, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-02-28 | Release date: | 2010-03-16 | Last modified: | 2014-10-08 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif. J.Biol.Chem., 285, 2010
|
|
3OXU
| Complement components factor H CCP19-20 and C3d in complex | Descriptor: | Complement C3, GLYCEROL, HF protein | Authors: | Morgan, H.P, Schmidt, C.Q, Guariento, M, Gillespie, D, Herbert, A.P, Mertens, H, Blaum, B.S, Svergun, D, Johansson, C.M, Uhrin, D, Barlow, P.N, Hannan, J.P. | Deposit date: | 2010-09-22 | Release date: | 2011-02-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for engagement by complement factor H of C3b on a self surface. Nat.Struct.Mol.Biol., 18, 2011
|
|
2YGO
| WIF domain-EGF-like domain 1 of human Wnt inhibitory factor 1 in complex with 1,2-dipalmitoylphosphatidylcholine | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... | Authors: | Malinauskas, T, Aricescu, A.R, Lu, W, Siebold, C, Jones, E.Y. | Deposit date: | 2011-04-19 | Release date: | 2011-07-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Modular Mechanism of Wnt Signaling Inhibition by Wnt Inhibitory Factor 1 Nat.Struct.Mol.Biol., 18, 2011
|
|
2YGN
| WIF domain of human Wnt inhibitory factor 1 in complex with 1,2- dipalmitoylphosphatidylcholine | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | Authors: | Malinauskas, T, Aricescu, A.R, Lu, W, Siebold, C, Jones, E.Y. | Deposit date: | 2011-04-19 | Release date: | 2011-07-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Modular Mechanism of Wnt Signaling Inhibition by Wnt Inhibitory Factor 1 Nat.Struct.Mol.Biol., 18, 2011
|
|
5CXT
| |
2YGQ
| WIF domain-epidermal growth factor (EGF)-like domains 1-3 of human Wnt inhibitory factor 1 in complex with 1,2- dipalmitoylphosphatidylcholine | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Malinauskas, T, Aricescu, A.R, Lu, W, Siebold, C, Jones, E.Y. | Deposit date: | 2011-04-19 | Release date: | 2011-07-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.951 Å) | Cite: | Modular Mechanism of Wnt Signaling Inhibition by Wnt Inhibitory Factor 1 Nat.Struct.Mol.Biol., 18, 2011
|
|
2YGP
| WIF domain-EGF-like domain 1 Met77Trp of human Wnt inhibitory factor 1 in complex with 1,2-dipalmitoylphosphatidylcholine | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Malinauskas, T, Aricescu, A.R, Lu, W, Siebold, C, Jones, E.Y. | Deposit date: | 2011-04-19 | Release date: | 2011-07-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.222 Å) | Cite: | Modular Mechanism of Wnt Signaling Inhibition by Wnt Inhibitory Factor 1 Nat.Struct.Mol.Biol., 18, 2011
|
|
3ZD2
| THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE | Descriptor: | 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 1 | Authors: | Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M. | Deposit date: | 2012-11-23 | Release date: | 2013-03-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
3ZD1
| STRUCTURE OF THE TWO C-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 2 | Descriptor: | 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 2 | Authors: | Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M. | Deposit date: | 2012-11-23 | Release date: | 2013-03-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
2H9E
| Crystal Structure of FXa/selectide/NAPC2 ternary complex | Descriptor: | ACETATE ION, Anti-coagulant protein C2, Coagulation factor X heavy chain, ... | Authors: | Murakami, M.T, Geiger, G, Tulinsky, A, Arni, R.K. | Deposit date: | 2006-06-09 | Release date: | 2007-02-13 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Intermolecular Interactions and Characterization of the Novel Factor Xa Exosite Involved in Macromolecular Recognition and Inhibition: Crystal Structure of Human Gla-domainless Factor Xa Complexed with the Anticoagulant Protein NAPc2 from the Hematophagous Nematode Ancylostoma caninum. J.Mol.Biol., 366, 2007
|
|
5DQE
| |
5DQ8
| |
1SI5
| Protease-like domain from 2-chain hepatocyte growth factor | Descriptor: | hepatocyte growth factor | Authors: | Kirchhofer, D, Yao, X, Peek, M, Eigenbrot, C, Lipari, M.T, Billeci, K.L, Maun, H.R, Moran, P, Santell, L, Lazarus, R.A. | Deposit date: | 2004-02-27 | Release date: | 2004-12-28 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Structural and functional basis of the serine protease-like hepatocyte growth factor beta-chain in Met binding and signaling J.Biol.Chem., 279, 2004
|
|
5FCR
| MOUSE COMPLEMENT FACTOR D | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Complement factor D, DIMETHYL SULFOXIDE, ... | Authors: | Mac Sweeney, A. | Deposit date: | 2015-12-15 | Release date: | 2016-10-26 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Small-molecule factor D inhibitors targeting the alternative complement pathway. Nat.Chem.Biol., 12, 2016
|
|
2LPN
| Solution Structure of N-Terminal domain of human Conserved Dopamine Neurotrophic Factor (CDNF) | Descriptor: | Cerebral dopamine neurotrophic factor | Authors: | Latge, C, Cabral, K.M.S, Foguel, D, Pires, J.R.M, Almeida, M.S. | Deposit date: | 2012-02-15 | Release date: | 2013-02-20 | Last modified: | 2013-05-22 | Method: | SOLUTION NMR | Cite: | (1)H-, (13)C- and (15)N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF). Biomol.Nmr Assign., 7, 2013
|
|
1JXS
| Solution Structure of the DNA-Binding Domain of Interleukin Enhancer Binding Factor | Descriptor: | interleukin enhancer binding factor | Authors: | Chuang, W.J, Liu, P.P, Li, C, Hsieh, Y.H, Chen, S.W, Chen, S.H, Jeng, W.Y. | Deposit date: | 2001-09-08 | Release date: | 2003-03-11 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the DNA-binding domain of interleukin enhancer binding factor 1 (FOXK1a) PROTEINS: STRUCT.,FUNCT.,GENET., 49, 2002
|
|
2J76
| Solution structure and RNA interactions of the RNA recognition motif from eukaryotic translation initiation factor 4B | Descriptor: | EUKARYOTIC TRANSLATION INITIATION FACTOR 4B | Authors: | Fleming, K, Ghuman, J, Yuan, X.M, Simpson, P, Szendroi, A, Matthews, S, Curry, S. | Deposit date: | 2006-10-06 | Release date: | 2008-10-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure and RNA Interactions of the RNA Recognition Motif from Eukaryotic Translation Initiation Factor 4B. Biochemistry, 42, 2003
|
|
1AXM
| HEPARIN-LINKED BIOLOGICALLY-ACTIVE DIMER OF FIBROBLAST GROWTH FACTOR | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ACIDIC FIBROBLAST GROWTH FACTOR | Authors: | DiGabriele, A.D, Lax, I, Chen, D.I, Svahn, C.M, Jaye, M, Schlessinger, J, Hendrickson, W.A. | Deposit date: | 1997-10-16 | Release date: | 1998-04-22 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of a heparin-linked biologically active dimer of fibroblast growth factor. Nature, 393, 1998
|
|
1AFC
| STRUCTURAL STUDIES OF THE BINDING OF THE ANTI-ULCER DRUG SUCROSE OCTASULFATE TO ACIDIC FIBROBLAST GROWTH FACTOR | Descriptor: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACIDIC FIBROBLAST GROWTH FACTOR | Authors: | Zhu, X, Hsu, B.T, Rees, D.C. | Deposit date: | 1993-07-13 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factor. Structure, 1, 1993
|
|
1CNT
| CILIARY NEUROTROPHIC FACTOR | Descriptor: | CILIARY NEUROTROPHIC FACTOR, SULFATE ION, YTTERBIUM (III) ION | Authors: | Mcdonald, N.Q, Panayotatos, N, Hendrickson, W.A. | Deposit date: | 1996-06-06 | Release date: | 1997-03-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of dimeric human ciliary neurotrophic factor determined by MAD phasing. EMBO J., 14, 1995
|
|
1ATZ
| HUMAN VON WILLEBRAND FACTOR A3 DOMAIN | Descriptor: | VON WILLEBRAND FACTOR | Authors: | Huizinga, E.G, Gros, P. | Deposit date: | 1997-08-15 | Release date: | 1998-02-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the A3 domain of human von Willebrand factor: implications for collagen binding. Structure, 5, 1997
|
|
1D5V
| SOLUTION STRUCTURE OF THE FORKHEAD DOMAIN OF THE ADIPOCYTE-TRANSCRIPTION FACTOR FREAC-11 (S12) | Descriptor: | S12 TRANSCRIPTION FACTOR (FKH-14) | Authors: | van Dongen, M.J.P, Cederberg, A, Carlsson, P, Enerback, S, Wikstrom, M. | Deposit date: | 1999-10-12 | Release date: | 2000-10-11 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure and dynamics of the DNA-binding domain of the adipocyte-transcription factor FREAC-11. J.Mol.Biol., 296, 2000
|
|
8CN9
| |
4NGA
| |
1BDA
| |