5FCR
MOUSE COMPLEMENT FACTOR D
Summary for 5FCR
Entry DOI | 10.2210/pdb5fcr/pdb |
Descriptor | Complement factor D, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... (6 entities in total) |
Functional Keywords | hydrolase |
Biological source | Mus musculus (House Mouse) |
Cellular location | Secreted: P03953 |
Total number of polymer chains | 4 |
Total formula weight | 102767.76 |
Authors | Mac Sweeney, A. (deposition date: 2015-12-15, release date: 2016-10-26, Last modification date: 2024-01-10) |
Primary citation | Maibaum, J.,Liao, S.M.,Vulpetti, A.,Ostermann, N.,Randl, S.,Rudisser, S.,Lorthiois, E.,Erbel, P.,Kinzel, B.,Kolb, F.A.,Barbieri, S.,Wagner, J.,Durand, C.,Fettis, K.,Dussauge, S.,Hughes, N.,Delgado, O.,Hommel, U.,Gould, T.,Mac Sweeney, A.,Gerhartz, B.,Cumin, F.,Flohr, S.,Schubart, A.,Jaffee, B.,Harrison, R.,Risitano, A.M.,Eder, J.,Anderson, K. Small-molecule factor D inhibitors targeting the alternative complement pathway. Nat.Chem.Biol., 12:1105-1110, 2016 Cited by PubMed: 27775713DOI: 10.1038/nchembio.2208 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
Download full validation report