3LYR

Human Early B-cell Factor 1 (EBF1) DNA-binding domain

Summary for 3LYR

• Entry DOI: 10.2210/pdb3lyr/pdb
• Descriptor: Transcription factor COE1, ZINC ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: immunoglobulin (ig)-like domain, structural genomics, structural genomics consortium, sgc, activator, developmental protein, dna-binding, metal-binding, nucleus, transcription, transcription regulation, zinc-finger, transcription activator
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (Potential): Q9UH73
• Total number of polymer chains: 1
• Total formula weight: 28195.97

Authors

Siponen, M.I.,Wisniewska, M.,Arrowsmith, C.H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Karlberg, T.,Kraulis, P.,Kotenyova, T.,Markova, N.,Moche, M.,Nordlund, P.,Nyman, T.,Persson, C.,Schuler, H.,Schutz, P.,Svensson, L.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Wahlberg, E.,Weigelt, J.,Welin, M.,Berglund, H.,Structural Genomics Consortium (SGC) (deposition date: 2010-02-28, release date: 2010-03-16, Last modification date: 2014-10-08)

• Primary citation: Siponen, M.I.,Wisniewska, M.,Lehtio, L.,Johansson, I.,Svensson, L.,Raszewski, G.,Nilsson, L.,Sigvardsson, M.,Berglund, H.; Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif.; J.Biol.Chem., 285:25875-25879, 2010; PubMed: 20592035; DOI: 10.1074/jbc.C110.150482

Experimental method

X-RAY DIFFRACTION (2.51 Å)