3LYR

Human Early B-cell Factor 1 (EBF1) DNA-binding domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1

Chain	Residue
A	HIS157
A	CYS161
A	CYS164
A	CYS170

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 251

Chain	Residue
A	ARG173
A	PRO177
A	SER178
A	ASP179

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NH4 A 252

Chain	Residue
A	ARG163

---

Functional Information from PROSITE/UniProt

site_id	PS01345
Number of Residues	10
Details	COE COE family signature. CSRCCDKKSC

Chain	Residue	Details
A	CYS161-CYS170

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Region: {"description":"Interaction with DNA","evidences":[{"source":"UniProtKB","id":"Q07802","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Site: {"description":"Interaction with DNA","evidences":[{"source":"UniProtKB","id":"Q07802","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"25114211","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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