2H9E
Crystal Structure of FXa/selectide/NAPC2 ternary complex
Summary for 2H9E
Entry DOI | 10.2210/pdb2h9e/pdb |
Descriptor | Coagulation factor X heavy chain, Coagulation factor X light chain, Anti-coagulant protein C2, ... (8 entities in total) |
Functional Keywords | factor xa, napc2, selectide, hydrolase-hydrolase inhibitor complex, blood clotting, hydrolase/hydrolase inhibitor |
Biological source | Ancylostoma caninum (dog hookworm) More |
Cellular location | Secreted: P00742 P00742 |
Total number of polymer chains | 4 |
Total formula weight | 53804.25 |
Authors | Murakami, M.T.,Geiger, G.,Tulinsky, A.,Arni, R.K. (deposition date: 2006-06-09, release date: 2007-02-13, Last modification date: 2017-10-18) |
Primary citation | Murakami, M.T.,Rios-Steiner, J.,Weaver, S.E.,Tulinsky, A.,Geiger, J.H.,Arni, R.K. Intermolecular Interactions and Characterization of the Novel Factor Xa Exosite Involved in Macromolecular Recognition and Inhibition: Crystal Structure of Human Gla-domainless Factor Xa Complexed with the Anticoagulant Protein NAPc2 from the Hematophagous Nematode Ancylostoma caninum. J.Mol.Biol., 366:602-610, 2007 Cited by PubMed: 17173931DOI: 10.1016/j.jmb.2006.11.040 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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