2YGP

WIF domain-EGF-like domain 1 Met77Trp of human Wnt inhibitory factor 1 in complex with 1,2-dipalmitoylphosphatidylcholine

Summary for 2YGP

Related2YGQ 2YGO 2YGN
DescriptorWNT INHIBITORY FACTOR 1, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywordssignaling protein, wnt signaling pathway, wnt antagonist, morphogen, cancer, glycosaminoglycan
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationSecreted Q9Y5W5
Total number of polymer chains1
Total molecular weight22271.65
Authors
Malinauskas, T.,Aricescu, A.R.,Lu, W.,Siebold, C.,Jones, E.Y. (deposition date: 2011-04-19, release date: 2011-07-13, Last modification date: 2020-07-29)
Primary citation
Malinauskas, T.,Aricescu, A.R.,Lu, W.,Siebold, C.,Jones, E.Y.
Modular Mechanism of Wnt Signaling Inhibition by Wnt Inhibitory Factor 1
Nat.Struct.Mol.Biol., 18:886-, 2011
PubMed: 21743455 (PDB entries with the same primary citation)
DOI: 10.1038/NSMB.2081
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.222 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.220110 0.7% 17.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
170383
PDB entries from 2020-10-28